CDK12 / CRKRS

cyclin-dependent kinase 12

Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.

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Products

Antibodies (17)

Type

Primary (17)

Target

CDK12 / CRKRS (17)

Reactivity

Human (17)

Mouse (8)

Rat (3)

Dog (1)

Monkey (1)

Application

IHC (1)

IHC-P (1)

WB (13)

ELISA (9)

IP (1)

Peptide-ELISA (1)

Host

rabbit (16)

mouse (1)

Product Group

Alzheimer's Disease (17)

PathPlus Neuro (1)

Isotype

IgG (13)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (16)

Clone

3C1 (1)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (9)

Epitope

aa1-30 (7)

Internal (1)

aa1-50 (1)

Publications

No (16)

Yes (1)

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PathPlus™ CDK12 / CRKRS Antibody (Internal) LS-A7350

Neuroscience

Fast Shipping

(5.0) Rating

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Dog, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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CDK12 / CRKRS Antibody (clone 3C1) LS-C105145

Antibody:

CDK12 / CRKRS Mouse anti-Human Monoclonal (3C1) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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CDK12 / CRKRS Antibody (aa1-30) LS-C99890

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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CDK12 / CRKRS Antibody (aa1-50) LS-C288466

(4.0) Rating

(1) Publication(s)

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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CDK12 / CRKRS Antibody LS-C673839

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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CDK12 / CRKRS Antibody (HRP) LS-C675149

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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CDK12 / CRKRS Antibody (Biotin) LS-C673838

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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CDK12 / CRKRS Antibody (FITC) LS-C675150

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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CDK12 / CRKRS Antibody LS-C749874

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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CDK12 / CRKRS Antibody (aa1-30) LS-C330372

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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CDK12 / CRKRS Antibody (aa1-30, Biotin) LS-C243905

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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CDK12 / CRKRS Antibody (aa1-30, FITC) LS-C243906

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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CDK12 / CRKRS Antibody (aa1-30, APC) LS-C243904

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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CDK12 / CRKRS Antibody (aa1-30, PE) LS-C243910

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

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CDK12 / CRKRS Antibody (aa1-30, Azide-free, HRP) LS-C247483

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

CDK12 / CRKRS Antibody LS-C779709

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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CDK12 / CRKRS Antibody LS-C802292

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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