CHI3L1 / YKL-40

chitinase 3-like 1 (cartilage glycoprotein-39)

Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

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Products

Antibodies (47)

ELISA Kits (22)

Proteins (12)

Type

Competitive EIA (1)

Custom (3)

Over-Expression Lysate (2)

Primary (47)

Recombinant (10)

Sandwich (17)

Sandwich CLIA (1)

Target

CHI3L1 / YKL-40 (81)

Reactivity

Human (37)

Mouse (23)

Rat (18)

Bovine (1)

Chimpanzee (3)

Gibbon (3)

Monkey (4)

Orangutan (3)

Pig (1)

Rabbit (3)

Application

IHC (10)

IHC-P (6)

WB (40)

ELISA (5)

IF (2)

Peptide-ELISA (1)

Host

rabbit (46)

mouse (1)

Product Group

IHCPlus (3)

Isotype

IgG (18)

Clonality

polyclonal pc (47)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (6)

96-Well Strip Plate (14)

APC (3)

APC Conjugated (4)

Biotin Conjugated (5)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (4)

Preservative Free (2)

Unconjugated (18)

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Epitope

aa112-356 (8)

aa112-377 (8)

aa117-364 (8)

aa198-247 (4)

Internal (1)

Publications

No (81)

Sample Type

Cell Culture Supernatants (6)

Cell Lysates (2)

Plasma (19)

Serum (19)

Tissue Homogenates (8)

Urine (2)

Tag

10His-SUMO, N-terminus + Myc, C-terminus (1)

6His, C-terminus (1)

GST (1)

His (3)

His,C-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (8)

Mouse (2)

Rat (1)

Source

293T Cells (1)

CHO Cells (1)

E. coli (4)

HEK 293 Cells (3)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (4)

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IHC-plus™ CHI3L1 / YKL-40 Antibody LS-B12326

(4.0) Rating

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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CHI3L1 / YKL-40 Antibody (aa198-247) LS-B8213

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Human Polyclonal (aa198-247) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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CHI3L1 / YKL-40 Antibody (Internal) LS-C354504

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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Mouse CHI3L1 / YKL-40 (Sandwich ELISA) ELISA Kit - LS-F2800

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$795

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Human CHI3L1 / YKL-40 (Sandwich ELISA) ELISA Kit - LS-F1020

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

32 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$534

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Rat CHI3L1 / YKL-40 (Sandwich ELISA) ELISA Kit - LS-F56116

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

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Rat CHI3L1 / YKL-40 (Sandwich ELISA) ELISA Kit - LS-F8893

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

3.12 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$750

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CHI3L1 / YKL-40 Antibody (aa112-356) LS-C294301

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Mouse Polyclonal (aa112-356) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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Human CHI3L1 / YKL-40 (Sandwich ELISA) ELISA Kit - LS-F4695

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

Select

Bovine CHI3L1 / YKL-40 (Sandwich ELISA) ELISA Kit - LS-F31810

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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CHI3L1 / YKL-40 Antibody LS-C485411

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$317; 100 µl/$375; 200 µl/$473

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Mouse CHI3L1 / YKL-40 (Sandwich ELISA) ELISA Kit - LS-F24915

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$632

Select

Human CHI3L1 / YKL-40 (Sandwich ELISA) ELISA Kit - LS-F24708

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Urine

Price:

1 Plate/$624

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Mouse CHI3L1 / YKL-40 Protein (Recombinant His) (Met1-Ala381) - LS-G98739

Source:

HEK 293 Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

42.3 kDa

Price:

100 µg/$721

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CHI3L1 / YKL-40 Antibody LS-C809553

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CHI3L1 / YKL-40 Antibody LS-C309898

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

CHI3L1 / YKL-40 Antibody (PE) LS-C649564

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

• Unconjugated
• PE

• Unconjugated
• PE

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CHI3L1 / YKL-40 Antibody (aa112-377) LS-B13928

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Human Polyclonal (aa112-377) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

Rat CHI3L1 / YKL-40 (Sandwich ELISA) ELISA Kit - LS-F17371

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Human CHI3L1 / YKL-40 (Sandwich ELISA) ELISA Kit - LS-F10139

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

46.875 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$744

Select

Human CHI3L1 / YKL-40 Protein (Recombinant His) - LS-G2177

Source:

CHO Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

10 µg/$292; 50 µg/$529

Select

Mouse CHI3L1 / YKL-40 Protein (Recombinant His) (aa112-356) - LS-G13843

Source:

E. coli

Tag:

His

Molecular Weight:

28.8 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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CHI3L1 / YKL-40 Antibody LS-C833976

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

CHI3L1 / YKL-40 Antibody LS-C834185

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

CHI3L1 / YKL-40 Antibody LS-C664561

Antibody:

CHI3L1 / YKL-40 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$331

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