CHI3L1 / YKL-40

chitinase 3-like 1 (cartilage glycoprotein-39)

Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

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Products

Proteins (12)

Type

Over-Expression Lysate (2)

Recombinant (10)

Target

CHI3L1 / YKL-40 (12)

Publications

No (12)

Tag

10His-SUMO, N-terminus + Myc, C-terminus (1)

6His, C-terminus (1)

GST (1)

His (3)

His,C-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (8)

Mouse (2)

Rat (1)

Source

293T Cells (1)

CHO Cells (1)

E. coli (4)

HEK 293 Cells (3)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (4)

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Mouse CHI3L1 / YKL-40 Protein (Recombinant His) (Met1-Ala381) - LS-G98739

Source:

HEK 293 Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

42.3 kDa

Price:

100 µg/$721

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Human CHI3L1 / YKL-40 Protein (Recombinant His) - LS-G2177

Source:

CHO Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

10 µg/$292; 50 µg/$529

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Mouse CHI3L1 / YKL-40 Protein (Recombinant His) (aa112-356) - LS-G13843

Source:

E. coli

Tag:

His

Molecular Weight:

28.8 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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Rat CHI3L1 / YKL-40 Protein (Recombinant His-T7) (aa117-364) - LS-G24333

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.0 kDa

Price:

10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225

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CHI3L1 / YKL-40 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118686

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.4 kDa

Price:

100 µg/$494

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Human CHI3L1 / YKL-40 Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (aa22-383) - LS-G56167

Source:

E. coli

Tag:

10His-SUMO, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human CHI3L1 / YKL-40 Protein (Recombinant GST) (Full Length) - LS-G27913

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

69 kDa

Price:

2 µg/$439

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Human CHI3L1 / YKL-40 Protein (Recombinant 6His, C-terminus) (Tyr22-Thr383) - LS-G38961

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

51.53kD

Price:

10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157

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Human CHI3L1 / YKL-40 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75012

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.4 kDa

Price:

20 µg/$150

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Human CHI3L1 / YKL-40 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65179

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.4 kDa

Price:

20 µg/$1,107

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Human CHI3L1 / YKL-40 Protein (Recombinant His,C-terminus) (Tyr22-Thr383) - LS-G138997

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

41.5 kDa

Price:

10 µg/$269; 50 µg/$368

Select

Human CHI3L1 / YKL-40 Protein (Recombinant His-T7) (aa112-377) - LS-G13842

Source:

E. coli

Tag:

His-T7

Molecular Weight:

33.0 kDa

Price:

10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107

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