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CLDN6 / Claudin 6

claudin 6

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

Gene Name: claudin 6
Family/Subfamily: Claudin , not assigned-Claudin
Synonyms: CLDN6, Claudin-6, Claudin 6, Skullin
Target Sequences: NM_021195 NP_067018.2 P56747

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
CLDN6 / Claudin 6 (4)
No (4)
6His-SUMO, N-terminus (1)
GST (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
CLDN6 / Claudin 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
23.1 kDa
20 µg/$150
CLDN6 / Claudin 6 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
100 µg/$1,128; 20 µg/$721
CLDN6 / Claudin 6 Protein - 12.5% SDS-PAGE of human CLDN6 stained with Coomassie Blue
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Wheat Germ Extract
GST
49.7 kDa
2 µg/$439
CLDN6 / Claudin 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.1 kDa
100 µg/$494
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).