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Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A3 form, is obtained as a binary complex of a procarboxypeptidase A with a proproteinase E. Mast cell carboxypeptidase A is a secretory granule metalloexopeptidase that has a pH optimum in the neutral to basic range. It resembles pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues.
Gene Name: | carboxypeptidase A3 (mast cell) |
Family/Subfamily: | Exopeptidase , Metallopeptidase M14 |
Synonyms: | CPA3, Carboxypeptidase A3, Mast cell carboxypeptidase A, MC-CPA, Tissue carboxypeptidase A |
Target Sequences: | NM_001870 NP_001861.2 P15088 |
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