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Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Gene Name: | connective tissue growth factor |
Family/Subfamily: | Hormone , not assigned-Hormone |
Synonyms: | CTGF, CCN family member 2, CCN2, IGFBP8, IGF-binding protein 8, NOV2, HCS24, IBP-8, IGFBP-8 |
Target Sequences: | NM_001901 NP_001892.1 P29279 |
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