CTSB / Cathepsin B

cathepsin B

Cathepsin B is a lysosomal cysteine proteinase synthesized as a zymogen of 39-47 kilodaltons (kD), which is subsequently converted into an active single- chain form of 33 kD (CB33) and, by additional processing, into the active 2-chain form containing a heavy chain of 27-29 kD (CB(27-29)) and a light chain of 4-6 kD. Cathepsin B is usually found in perinuclear lysosomes of epithelial cells of normal organs and non-malignant tumors, but is associated with the plasma membranes of many solid organ malignant tumors. Cathepsin B, a marker of the dedifferentiated chondrocyte phenotype, has been shown to contribute to cartilage destruction in osteoarthritis and pathological proteolysis in rheumatoid arthritis and cancer. Increased or altered CB expression has been documented in a variety of tumor cells. It has also been suggested that a cat B-mitochondrial apoptotic pathway plays a pivotal role in TNF-alpha-induced hepatocyte apoptosis and liver injury.

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Products

ELISA Kits (26)

Type

Custom (6)

Sandwich (19)

Sandwich CLIA (1)

Target

CTSB / Cathepsin B (26)

Reactivity

Human (9)

Mouse (5)

Rat (5)

Chicken (2)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Product Group

Coronavirus Detection (25)

ELISA Kits for Associated Targets (25)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (5)

96-Well Strip Plate (19)

Publications

No (26)

Sample Type

Cell Culture Supernatants (4)

Cell Lysates (2)

Cell Supernatant (1)

Plasma (16)

Serum (16)

Tissue Homogenates (6)

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Human CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F1026

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

250 - 16000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$534

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Rat CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F9334

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F2617

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$559

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Mouse CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F24717

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$624

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Human CTSB / Cathepsin B (Custom ELISA) ELISA Kit - LS-F474

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$534

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Human CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F2616

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$559

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Rat CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F54723

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

18.75 - 1200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$897

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Human CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F74654

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$598

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Human CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F6665

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$730

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Mouse CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F9324

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$748

Select

Chicken CTSB / Cathepsin B (Custom ELISA) ELISA Kit - LS-F14485

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Bovine CTSB / Cathepsin B (Custom ELISA) ELISA Kit - LS-F14486

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Rat CTSB / Cathepsin B (Custom ELISA) ELISA Kit - LS-F14487

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse CTSB / Cathepsin B (Custom ELISA) ELISA Kit - LS-F14488

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Pig CTSB / Cathepsin B (Custom ELISA) ELISA Kit - LS-F14489

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F21477

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Rat CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F21653

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F24372

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$624

Select

Human CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F34520

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F34521

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human CTSB / Cathepsin B (CLIA) ELISA Kit - LS-F29081

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Chicken CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F42054

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F42055

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Porcine CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F42056

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Rabbit CTSB / Cathepsin B (Sandwich ELISA) ELISA Kit - LS-F42057

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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