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CTSK / Cathepsin K

cathepsin K

CTSK / Cathepsin K is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

Gene Name: cathepsin K
Family/Subfamily: Protease , Cysteine C1
Synonyms: CTSK, Cathepsin K, Cathepsin K (pycnodysostosis), Cathepsin O1, Cathepsin O2, Cathepsin X, CTSO2, PKND, Procathepsin K, PYCD, Cathepsin O, CTS02, CTSO1
Target Sequences: NM_000396 NP_000387.1 P43235

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Products
Antibodies (118)
Primary (118)
CTSK / Cathepsin K (118)
Human (71)
Mouse (25)
Rat (23)
Bat (3)
Bovine (12)
Cow (8)
Dog (12)
Duck (1)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (4)
Pig (27)
Rabbit (3)
Rhesus monkey (16)
Zebrafish (3)
IHC (17)
IHC-P (12)
WB (112)
Flo (2)
ELISA (18)
ICC (8)
IF (2)
IP (9)
Peptide-ELISA (2)
rabbit (89)
mouse (28)
goat (1)
Product Group
IHCPlus (3)
IgG (33)
IgG2a,k (7)
IgG2b (1)
IgG2b,k (8)
monoclonal mc (27)
polyclonal pc (91)
2F1 (1)
CTSK/2791 (3)
APC (9)
APC Conjugated (11)
Azide-free (1)
Biotin Conjugated (14)
BSA-free (1)
Cy3 Conjugated (9)
Cy7 Conjugated (9)
FITC Conjugated (14)
HRP Conjugated (14)
PE Conjugated (11)
Ready-to-Use (1)
Unconjugated (36)
aa116-329 (16)
aa115-329 (10)
aa113-316 (8)
aa54-317 (8)
aa71-319 (8)
aa77-318 (8)
aa90-318 (8)
aa163-212 (4)
Internal (1)
aa207-237 (1)
aa220-329 (1)
aa31-43 (1)
aa97-126 (1)
No (118)
CTSK / Cathepsin K Antibody - Anti-CTSK / Cathepsin K antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CTSK / Cathepsin K Mouse anti-Human Monoclonal (2F1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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CTSK / Cathepsin K Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$657
CTSK / Cathepsin K Antibody - Western blot of recombinant CTSK / Cathepsin K.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTSK / Cathepsin K Rabbit anti-Mouse Polyclonal (aa113-316) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
CTSK / Cathepsin K Antibody - Antibody (1 ug/ml) staining of Human Lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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CTSK / Cathepsin K Goat anti-Human Polyclonal (aa31-43) Antibody
Human
ELISA, Peptide-ELISA, WB
Unconjugated
100 µg/$503
CTSK / Cathepsin K Antibody - Formalin-fixed and paraffin-embedded human breast carcinoma with CTSK Antibody (Center R222), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal (aa207-237) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CTSK / Cathepsin K Antibody - CTSK Antibody (Center E112) immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal (aa97-126) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CTSK / Cathepsin K Antibody - Western blot analysis of extracts of Mouse uterus cells.
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 100 µl/$409
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CTSK / Cathepsin K Mouse anti-Human Monoclonal (aa220-329) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$705
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CTSK / Cathepsin K Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
100 µl/$904
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CTSK / Cathepsin K Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
100 µl/$904
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CTSK / Cathepsin K Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
100 µl/$904
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CTSK / Cathepsin K Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
100 µl/$904
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CTSK / Cathepsin K Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
100 µl/$904
CTSK / Cathepsin K Antibody - Immunohistochemistry of paraffin-embedded mouse brain using CTSK antibodyat dilution of 1:100 (40x lens).
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal Antibody
Duck, Mouse, Rat
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CTSK / Cathepsin K Antibody - Western blot of recombinant CTSK / Cathepsin K.
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal (aa54-317) Antibody
Pig, Human
WB
Unconjugated
100 µl/$299; 200 µl/$336; 500 µl/$462; 1 ml/$525; 2 ml/$677; 5 ml/$1,136
CTSK / Cathepsin K Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using Ctsk Antibody at dilution of 1:50
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CTSK / Cathepsin K Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
CTSK / Cathepsin K Antibody - Western blot of recombinant CTSK / Cathepsin K.
Select
CTSK / Cathepsin K Rabbit anti-Human Polyclonal (aa115-329) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
CTSK / Cathepsin K Antibody - CTSK / Cathepsin K antibody Western blot of Fetal Liver lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal (aa163-212) Antibody
Rat, Human
WB
Unconjugated
100 µl/$424
CTSK / Cathepsin K Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal (aa115-329) Antibody
Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CTSK / Cathepsin K Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CTSK / Cathepsin K Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
CTSK / Cathepsin K Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
CTSK / Cathepsin K Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
CTSK / Cathepsin K Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
CTSK / Cathepsin K Antibody - Cathepsin K was detected in paraffin-embedded sections of human osteosarcoma tissues using rabbit anti- Cathepsin K Antigen Affinity purified polyclonal antibody at 1 ug/mL. The immunohistochemical section was developed using SABC method.
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal (aa115-329) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CTSK / Cathepsin K Antibody - Immunohistochemistry of paraffin-embedded Mouse brain using CTSK Polyclonal Antibody at dilution of 1:100 (40x lens).
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CTSK / Cathepsin K Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).