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CXCR1

chemokine (C-X-C motif) receptor 1

CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

Gene Name: chemokine (C-X-C motif) receptor 1
Family/Subfamily: GPCR , Chemokine
Synonyms: CXCR1, C-C, Chemokine c-x-c receptor 1, CKR-1, CMKAR1, CD128, CD181, CD181 antigen, CXCR-1, CXC-R1, IL-8R A, Il8 receptor a, Interleukin 8 receptor a, Interleukin 8 receptor alpha, Interleukin 8 receptor, alpha, Interleukin-8 receptor type A, IL8RBA, Interleukin-8 receptor type 1, C-C-CKR-1, CDw128a, IL-8 receptor type 1, IL8R1, IL8RA
Target Sequences: NM_000634 NP_000625.1 P25024

Publications (3)

1
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-?B-Snail signaling in glioma. Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, Wang X, Zhao C, Zhang H, Wang Y. Cancer biology & therapy. 2015 16:898-911. (IHC, WB; Human) [Full Text Article] [PubMed:25870011] [PMC:PMC4623112] Related Antibodies: LS-C178869.
2
Inflammatory Bowel Disease Types Differ in Markers of Inflammation, Gut Barrier and in Specific Anti-Bacterial Response. Stepan Coufal, Natalie Galanova, Lukas Bajer, Zuzana Gajdarova, Dagmar Schierova, Zuzana Jiraskova Zakostelska, Klara Kostovcikova, Zuzana Jackova, Zuzana Stehlikova, Pavel Drastich, Helena Tlaskalova-Hogenova, Miloslav Kverka. Cells. 2019 Jul;8:719. [Full Text Article] [PubMed:31337064] [PMC:PMC6678638]
3
ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit. Wilson BJ, Saab KR, Ma J, Schatton T, P[Character fc]tz P, Zhan Q, Murphy GF, Gasser M, Waaga-Gasser AM, Frank NY, Frank MH. Cancer research. Aug;74:4196-207. [Full Text Article] [PubMed:24934811] [PMC:PMC4119553] Related Antibodies: LS-A806.

☰ Filters
Antibodies (16)
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CXCR1 (35)
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monoclonal mc (1)
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HEK 293 Cells (1)
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CXCR1 Antibody - Anti-CXCR1 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CXCR1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
CXCR1 Antibody - Human Liver, Macrophages: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
CXCR1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
CXCR1 Antibody - Anti-CXCR1 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
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Fast Shipping
CXCR1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
CXCR1 Antibody
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CXCR1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC-P, WB
Unconjugated
100 µl/$332
CXCR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CXCR1 Antibody - Western blot of 15 ug of whole cell lysate from Raw cells with antibody at 2 ug/ml dilution.
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CXCR1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
0.1 mg/$386
CXCR1 Antibody - CXCR1 antibody. IHC(P): Human Lung Cancer Tissue.
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CXCR1 Rabbit anti-Human Polyclonal (aa24-38) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CXCR1 Antibody - Western blot analysis using CD181 mAb against HEK293 (1) and CD181-hIgGFc transfected HEK293 (2) cell lysate.
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CXCR1 Mouse anti-Human Monoclonal (2B8A1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$459
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CXCR1 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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CXCR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
CXCR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$782
CXCR1 Antibody - Immunohistochemistry of paraffin-embedded Rat lung using CXCR1 Polyclonal Antibody at dilution of 1:100 (40x lens).
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CXCR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CXCR1 Antibody - Western blot analysis of CXCR1 using K562 whole lysates.
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CXCR1 Rabbit anti-Human Polyclonal (aa1-22) Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CXCR1 Rabbit anti-Human Polyclonal Antibody
Human
IP, Peptide-ELISA, WB
Unconjugated
100 µg/$351
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CXCR1 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, Peptide-ELISA
Unconjugated
100 µg/$357
CXCR1 Antibody - Antibody (0.3µg/ml) staining of Human Breast cancer lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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CXCR1 Goat anti-Human Polyclonal (aa26-38) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
CXCR1 Antibody - Anti-CXCR1 rabbit polyclonal antibody at 1:500 dilution. Lane A: HepG2 Whole Cell lysate. Lane B: Mouse small intestine tissue lysate. Lane C: Mouse spleen tissue lysate. Lysates/proteins at 30 ug per Lane. Secondary: Goat Anti-Rabbit-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 40 kDa.
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CXCR1 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
WB
Unconjugated, Preservative Free
100 µl/$412
CXCR1 Antibody - Western blot analysis of CD181 expression in HEK293T (A); NIH3T3 (B); H9C2 (C) whole cell lysates.
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CXCR1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
CXCR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$764
CXCR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
CXCR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$715
CXCR1 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
CXCR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CXCR1 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CXCR1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Viewing 1-25 of 35 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).