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Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
CXCR1
chemokine (C-X-C motif) receptor 1
CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
| Gene Name: | chemokine (C-X-C motif) receptor 1 |
| Family/Subfamily: | GPCR , Chemokine |
| Synonyms: | CXCR1, C-C, Chemokine c-x-c receptor 1, CKR-1, CMKAR1, CD128, CD181, CD181 antigen, CXCR-1, CXC-R1, IL-8R A, Il8 receptor a, Interleukin 8 receptor a, Interleukin 8 receptor alpha, Interleukin 8 receptor, alpha, Interleukin-8 receptor type A, IL8RBA, Interleukin-8 receptor type 1, C-C-CKR-1, CDw128a, IL-8 receptor type 1, IL8R1, IL8RA |
| Target Sequences: | NM_000634 NP_000625.1 P25024 |
Publications (3)
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