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LY75/CD205/DEC-205 is an integral membrane protein homologous to the macrophage mannose receptor and functions as an antigen-uptake receptor on dendritic cells. DEC-205 is rapidly taken up by means of coated pits and vesicles and is delivered to a multivesicular endosomal compartment that resembles the MHC class II-containing vesicles.
Gene Name: | lymphocyte antigen 75 |
Synonyms: | LY75, CD205, CLEC13B, CD205 antigen, LY-75, Lymphocyte antigen 75, DEC-205, gp200-MR6 |
Target Sequences: | NM_002349 NP_002340.2 O60449 |
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