DUSP4 / MKP2

dual specificity phosphatase 4

TYP / DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

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Products

ELISA Kits (6)

Type

Cell-Based (1)

Custom (3)

Sandwich (2)

Target

DUSP4 / MKP2 (6)

Reactivity

Human (3)

Mouse (2)

Rat (2)

Chicken (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (5)

Publications

No (6)

Sample Type

Adherent Cell Cultures (1)

Plasma (2)

Serum (2)

Tissue Homogenates (1)

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Human DUSP4 / MKP2 (Sandwich ELISA) ELISA Kit - LS-F16494

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human DUSP4 / MKP2 (Sandwich ELISA) ELISA Kit - LS-F32918

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse/Human/Rat DUSP4 / MKP2 (Cell-Based ELISA) ELISA Kit - LS-F3171

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Chicken DUSP4 / MKP2 (Custom ELISA) ELISA Kit - LS-F16495

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Rat DUSP4 / MKP2 (Custom ELISA) ELISA Kit - LS-F16496

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse DUSP4 / MKP2 (Custom ELISA) ELISA Kit - LS-F16497

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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