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F2RL2 / PAR3

coagulation factor II (thrombin) receptor-like 2

F2RL2 / PAR3 is a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms.

Gene Name: coagulation factor II (thrombin) receptor-like 2
Family/Subfamily: GPCR , Proteinase-activated
Synonyms: F2RL2, PAR-3, Thrombin receptor-like 2, PAR3, Protease-activated receptor 3
Target Sequences: NM_004101 NP_004092.1 O00254

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Proteins (2)
Over-Expression Lysate (2)
F2RL2 / PAR3 (2)
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Myc-DDK (Flag) (2)
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293T Cells (1)
HEK 293 Cells (1)
F2RL2 / PAR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
42.3 kDa
20 µg/$150
F2RL2 / PAR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.3 kDa
100 µg/$494
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).