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The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer.
Gene Name: | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) |
Synonyms: | FABP3, H-FABP, Fatty acid-binding protein 3, M-FABP, MDGI, O-FABP, FABP11, Fatty acid binding protein 11 |
Target Sequences: | NM_004102 NP_004093.1 P05413 |
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