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FGF19 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development.
Gene Name: | fibroblast growth factor 19 |
Family/Subfamily: | HBGF , not assigned-HBGF |
Synonyms: | FGF19, Fibroblast growth factor 19, FGF-19 |
Target Sequences: | NM_005117 NP_005108.1 O95750 |
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