Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
FLG / Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.
Gene Name: | filaggrin |
Synonyms: | FLG, ATOD2, Epidermal filaggrin, Filaggrin |
Target Sequences: | NM_002016 NP_002007.1 P20930 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.