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FLG / Filaggrin

filaggrin

FLG / Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.

Gene Name: filaggrin
Synonyms: FLG, ATOD2, Epidermal filaggrin, Filaggrin
Target Sequences: NM_002016 NP_002007.1 P20930

Publications (1)

1
Verbascoside Alleviates Atopic Dermatitis-Like Symptoms in Mice via Its Potent Anti-Inflammatory Effect. Yongxi Li, Haiyang Yu, Yan Jin, Min Li, Caijie Qu. International archives of allergy and immunology. 2018 March;175:220-230. [Full Text Article] [PubMed:29587260]

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Proteins (4)
Recombinant (4)
FLG / Filaggrin (4)
No (4)
6His, N-terminus (2)
His-GST (1)
His-SUMO (1)
Human (3)
Mouse (1)
Baculovirus (1)
E. coli (2)
Yeast (1)
Purified (1)
FLG / Filaggrin Protein
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Yeast
6His, N-terminus
26.7 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
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E. coli
His-SUMO
40.7 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
FLG / Filaggrin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Baculovirus
6His, N-terminus
100 µg/$1,164; 20 µg/$475; 1 mg/$2,187
FLG / Filaggrin Protein - Recombinant Filaggrin By SDS-PAGE
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E. coli
His-GST
55.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).