FOLH1 / PSMA

folate hydrolase (prostate-specific membrane antigen) 1

FOLH1 / PSMA is a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.

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Products

Proteins (18)

Type

Over-Expression Lysate (8)

Recombinant (10)

Target

FOLH1 / PSMA (18)

Publications

No (18)

Tag

6His, N-terminus (2)

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His,N-terminus (1)

His-T7 (1)

His-T7, N-terminus (1)

Myc-DDK (Flag) (8)

Myc-DDK (Flag), C-terminus (1)

Species

Human (12)

Mouse (3)

Pig (1)

Source

293T Cells (5)

E. coli (4)

HEK 293 Cells (4)

Human (1)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (3)

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Human FOLH1 / PSMA Protein (Recombinant 6His, N-terminus) (aa48-750) - LS-G22554

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

83.2 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human FOLH1 / PSMA Protein (Recombinant GST) (Full Length) - LS-G28505

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

107 kDa

Price:

10 µg/$479; 25 µg/$670

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Human FOLH1 / PSMA Protein (Recombinant His, N-Terminal) (Ala274-Leu587) - LS-G24908

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

39.1 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human FOLH1 / PSMA Protein (Recombinant Myc-DDK (Flag), C-terminus) (Full Length) - LS-G66674

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag), C-terminus

Molecular Weight:

84.2 kDa

Price:

20 µg/$1,107

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Human FOLH1 / PSMA Protein (Recombinant GST, N-terminus) (aa547-656) - LS-G58598

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse FOLH1 / PSMA Protein (Recombinant His) (Ile44-Ala752) - LS-G98155

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

81.8 kDa

Price:

100 µg/$1,108; 1 mg/$6,025

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Human FOLH1 / PSMA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78267

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

80.4 kDa

Price:

20 µg/$150

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Human FOLH1 / PSMA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78268

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.2 kDa

Price:

20 µg/$215

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Human FOLH1 / PSMA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78269

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.2 kDa

Price:

20 µg/$215

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Human FOLH1 / PSMA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78270

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.9 kDa

Price:

20 µg/$215

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Human FOLH1 / PSMA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78271

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.5 kDa

Price:

20 µg/$150

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Mouse FOLH1 / PSMA Protein (Recombinant 6His, N-terminus) - LS-G146265

Source:

Human

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

80.7 kDa

Price:

10 µg/$294; 50 µg/$460

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FOLH1 / PSMA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116608

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.2 kDa

Price:

100 µg/$710

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Human FOLH1 / PSMA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121614

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

80.4 kDa

Price:

100 µg/$494

Select

FOLH1 / PSMA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G130954

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.5 kDa

Price:

100 µg/$494

Select

Human FOLH1 / PSMA Protein (Recombinant His,N-terminus) (Lys44-Ala750) - LS-G140568

Source:

Mammalian Cells

Tag:

His,N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

80.6 kDa

Price:

10 µg/$344; 50 µg/$584

Select

Pig FOLH1 / PSMA Protein (Recombinant His-T7) (aa275-588) - LS-G24909

Source:

E. coli

Tag:

His-T7

Molecular Weight:

39.1 kDa

Price:

10 µg/$289; 50 µg/$490; 100 µg/$782; 200 µg/$977; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304

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Mouse FOLH1 / PSMA Protein (Recombinant His-T7, N-terminus) (Arg536-Ala752) - LS-G133482

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

28.7kDa

Price:

10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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