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FOS / c-FOS

FBJ murine osteosarcoma viral oncogene homolog

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

Gene Name: FBJ murine osteosarcoma viral oncogene homolog
Synonyms: FOS, Activator protein 1, AP-1, Cellular oncogene c-fos, Cellular oncogene fos, Proto-oncogene c-Fos, v-fos, C-FOS, G0s7, p55
Target Sequences: NM_005252 NP_005243.1 P01100

Publications (3)

1
Perineural pretreatment of bee venom attenuated the development of allodynia in the spinal nerve ligation injured neuropathic pain model; an experimental study. Koh WU, Choi SS, Lee JH, Lee SH, Lee SK, Lee YK, Leem JG, Song JG, Shin JW. BMC complementary and alternative medicine. 2014 14:431. (IHC; Human) [Full Text Article] [PubMed:25366818] [PMC:PMC4246472] Related Antibodies: LS-C93966.
2
Decreased neuroinflammation correlates to higher vagus nerve activity fluctuations in near-term ovine fetuses: a case for the afferent cholinergic anti-inflammatory pathway?. Frasch MG, Szynkaruk M, Prout AP, Nygard K, Cao M, Veldhuizen R, Hammond R, Richardson BS. Journal of neuroinflammation. 2016 13:103. (WB; Human) [Full Text Article] [PubMed:27165310] [PMC:PMC4894374] Related Antibodies: LS-C77393.
3
c-FOS drives reversible basal to squamous cell carcinoma transition. François Kuonen, Nancy Yanzhe Li, Daniel Haensel, Tiffany Patel, Sadhana Gaddam, Laura Yerly, Kerri Rieger, Sumaira Aasi, Anthony E Oro. Cell reports. 2021 October;37:109774. [Full Text Article] [PubMed:34610301] [PMC:PMC8515919] Related Antibodies: LS-B14369.

☰ Filters
Antibodies (193)
ELISA Kits (25)
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FOS / c-FOS (225)
Human (194)
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FOS / c-FOS Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Neuroscience
FOS / c-FOS Goat anti-Human Polyclonal (aa283-295) Antibody
Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
FOS / c-FOS Antibody - Anti-FOS / c-FOS antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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FOS / c-FOS Mouse anti-Human Monoclonal (1H8) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Select
FOS / c-FOS Mouse anti-Human Monoclonal (aa128-152) (2G9C3) Antibody
Chicken, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
IF, WB
Unconjugated
100 µg/$762
FOS / c-FOS Antibody - Anti-FOS / c-FOS antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Neuroscience
FOS / c-FOS Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Select
FOS / c-FOS Sheep anti-Human Polyclonal (aa300-380) Antibody
Mouse, Rat, Human
WB
Unconjugated
500 µg/$393
FOS / c-FOS Antibody - Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-FOS mAb.
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FOS / c-FOS Mouse anti-Human Monoclonal (554C1a) Antibody
Human
DB, ICC, IF, WB
Unconjugated
100 µg/$486
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FOS / c-FOS Sheep anti-Human Polyclonal (aa4-17) Antibody
Rat, Human
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
500 µg/$832
FOS / c-FOS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FOS / c-FOS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
FOS / c-FOS Antibody - Immunohistochemistry of paraffin-embedded mouse brain tissue slide using c-FOS antibody at dilution of 1:400
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FOS / c-FOS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
FOS / c-FOS Antibody - Anti-FOS / c-FOS antibody IHC of human skin, epidermis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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FOS / c-FOS Rabbit anti-Human Polyclonal (aa201-250) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
FOS / c-FOS Antibody - Immunohistochemical analysis of c-FOS staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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FOS / c-FOS Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
FOS / c-FOS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
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FOS / c-FOS Mouse anti-Bovine Monoclonal Antibody
Mouse, Bovine, Rat, Human
IF, IHC, WB
Unconjugated
100 µl/$469
FOS / c-FOS Antibody - Immunohistochemical analysis of c-FOS staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
FOS / c-FOS Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
FOS / c-FOS Antibody - Immunohistochemical analysis of c-FOS (pS362) staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
FOS / c-FOS Rabbit anti-Human Polyclonal (pS362) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$315
FOS / c-FOS Antibody - IHC of paraffin-embedded Human liver tissue using anti-FOS mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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FOS / c-FOS Mouse anti-Human Monoclonal (OTI3B8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
FOS / c-FOS Antibody - IHC of paraffin-embedded Human prostate tissue using anti-FOS mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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FOS / c-FOS Mouse anti-Human Monoclonal (OTI2D2) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$434
FOS / c-FOS Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
FOS / c-FOS Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
60 µl/$460
FOS / c-FOS Antibody - IHC of paraffin-embedded colon cancer tissues using FOS mouse monoclonal antibody with DAB staining.
Select
FOS / c-FOS Mouse anti-Human Monoclonal (2G2) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
FOS / c-FOS Antibody - FOS / c-FOS antibody Western blot of Fetal Muscle lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FOS / c-FOS Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
FOS / c-FOS Antibody - 1:100 staining human liver tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
FOS / c-FOS Rabbit anti-Human Polyclonal (pSer362) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
FOS / c-FOS Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$412
FOS / c-FOS Antibody - c-Fos Antibody in Immunohistochemistry (IHC)
Select
FOS / c-FOS Mouse anti-Human Monoclonal (2G2) Antibody
Human
Flo, IHC, WB
Unconjugated
100 µl/$503
FOS / c-FOS Antibody - Immunohistochemical staining of paraffin-embedded human melanoma using anti-FOS clone UMAB221 at 1:200 dilution of 0.5 mg/mL and detection with Polink2 Broad HRP DAB.requires heat-induced epitope retrieval with ACCEL. (pH8.7) biocare pressure cooker. The image shows nuclear staining in tumor cells.
Select
FOS / c-FOS Mouse anti-Human Monoclonal (UMAB221) Antibody
Human
IHC, PMA, WB
Unconjugated
100 µl/$493
Viewing 1-25 of 225 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).