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FOXO3 / FOXO3A

forkhead box O3

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

Gene Name: forkhead box O3
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: FOXO3, AF6q21, AF6q21 protein, Forkhead box O3, Forkhead box O3A, FOXO3A, FKHRL1P2, Forkhead box protein O3, FOXO2, FKHRL1
Target Sequences: NM_001455 NP_001446.1 O43524

Publications (1)

1
Impact of miRNA-mRNA Profiling and Their Correlation on Medulloblastoma Tumorigenesis. Kumar V, Kumar V, Chaudhary AK, Coulter DW, McGuire T, Mahato RI. Molecular therapy. Nucleic acids. 2018 September;12:490-503. [Full Text Article] [PubMed:30195786] [PMC:PMC6070673]

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Products
ELISA Kits (20)
Cell-Based (1)
Cell-Based Phosphorylation (1)
Competitive EIA (1)
DNA Binding (1)
DNA Binding Phosphorylation (1)
Sandwich (14)
Sandwich CLIA (1)
FOXO3 / FOXO3A (20)
Human (11)
Mouse (8)
Rat (3)
Chicken (1)
Monkey (1)
Porcine (1)
Rabbit (1)
Sheep (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (3)
96-Well Strip Plate (14)
No (20)
Adherent Cell Cultures (2)
Cell Lysates (4)
Nuclear Lysates (2)
Plasma (9)
Serum (9)
Tissue Homogenates (5)
FOXO3 / FOXO3A ELISA Kit
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DNA Binding
12 x 8-Well Microstrips
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$694
FOXO3 / FOXO3A ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FOXO3 / FOXO3A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FOXO3 / FOXO3A ELISA Kit
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Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FOXO3 / FOXO3A ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
FOXO3 / FOXO3A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FOXO3 / FOXO3A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FOXO3 / FOXO3A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FOXO3 / FOXO3A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FOXO3 / FOXO3A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
FOXO3 / FOXO3A ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
FOXO3 / FOXO3A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
FOXO3 / FOXO3A ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
FOXO3 / FOXO3A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FOXO3 / FOXO3A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$958
FOXO3 / FOXO3A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$764
FOXO3 / FOXO3A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FOXO3 / FOXO3A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$782
FOXO3 / FOXO3A ELISA Kit
Select
DNA Binding Phosphorylation
12 x 8-Well Microstrips
Mouse, Human
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$735
FOXO3 / FOXO3A ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).