GAD1 / GAD67

glutamate decarboxylase 1 (brain, 67kDa)

GAD1 / GAD67 is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

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Products

Proteins (11)

Type

Over-Expression Lysate (2)

Recombinant (9)

Target

GAD1 / GAD67 (11)

Publications

No (11)

Tag

GST (2)

His (2)

His,C-terminus (1)

His-GST (1)

His-S (2)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (2)

Rat (1)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (2)

Insect Cells (1)

Wheat Germ Extract (2)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (1)

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Human GAD1 / GAD67 Protein (Recombinant His) - LS-G3053

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Mouse GAD1 / GAD67 Protein (Recombinant His-S) (aa1-97) - LS-G15088

Source:

E. coli

Tag:

His-S

Molecular Weight:

16.4 kDa

Price:

10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796

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Human GAD1 / GAD67 Protein (Recombinant His) - LS-G2857

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human GAD1 / GAD67 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65731

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.7 kDa

Price:

20 µg/$1,107

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GAD1 / GAD67 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99177

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.7 kDa

Price:

100 µg/$494

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Human GAD1 / GAD67 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76168

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.7 kDa

Price:

20 µg/$150

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Human GAD1 / GAD67 Protein (Recombinant His,C-terminus) (Met1-Leu594) - LS-G140734

Source:

Insect Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

68.3 kDa

Price:

50 µg/$721

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Human GAD1 / GAD67 Protein (Recombinant GST) (Full Length) - LS-G28557

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

91.08 kDa

Price:

10 µg/$479; 25 µg/$670

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Human GAD1 / GAD67 Protein (Recombinant GST) (Full Length) - LS-G28559

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

91.08 kDa

Price:

10 µg/$479; 25 µg/$670

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Mouse GAD1 / GAD67 Protein (Recombinant His-GST) (aa1-97) - LS-G15089

Source:

E. coli

Tag:

His-GST

Molecular Weight:

42.6 kDa

Price:

10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796

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Rat GAD1 / GAD67 Protein (Recombinant His-S) (aa1-97) - LS-G15090

Source:

E. coli

Tag:

His-S

Molecular Weight:

16.3 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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