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Vector Laboratories, Inc.
6737 Mowry Ave
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GCG / Glucagon

Glucagon

Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis.GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability.Oxyntomodulin significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness.Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.

Gene Name: Glucagon
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: GCG, GLP2, Glucagon, Glucagon-like peptide 2, GRPP, Glicentin-related polypeptide, GLP1, Glucagon-like peptide 1
Target Sequences: NM_002054 NP_002045.1 P01275

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Products
ELISA Kits (33)
Cell-Based (1)
Competitive EIA (18)
Custom (4)
Sandwich (10)
GCG / Glucagon (33)
Human (12)
Mouse (7)
Rat (7)
Chicken (2)
Dog (1)
Monkey (1)
Pig (2)
Porcine (1)
Sheep (1)
96-Well Microplate (5)
96-Well Strip Plate (28)
No (33)
Adherent Cell Cultures (1)
Cell Culture Supernatants (7)
Cell Lysates (3)
Plasma (24)
Serum (25)
Tissue Homogenates (8)
GCG / Glucagon ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
18.52 - 1500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
GCG / Glucagon ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
GCG / Glucagon ELISA Kit
Select
Competitive EIA
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$505
GCG / Glucagon ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Chicken
18.52 - 1500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$750
GCG / Glucagon ELISA Kit
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Sandwich
96-Well Microplate
Human
2.032 - 130 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
GCG / Glucagon ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
GCG / Glucagon ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
GCG / Glucagon ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
18.52 - 1500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$750
GCG / Glucagon ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
GCG / Glucagon ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
GCG / Glucagon ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
GCG / Glucagon ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
GCG / Glucagon ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GCG / Glucagon ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GCG / Glucagon ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.3 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
GCG / Glucagon ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Monkey
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$565
GCG / Glucagon ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Porcine
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$565
GCG / Glucagon ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
GCG / Glucagon ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
12.9 - 200 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$968
GCG / Glucagon ELISA Kit
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Sandwich
96-Well Microplate
Human
150 - 20000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$760
GCG / Glucagon ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Pig
125 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$968
GCG / Glucagon ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GCG / Glucagon ELISA Kit
Select
Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$610
GCG / Glucagon ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
GCG / Glucagon ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
18.52 - 1500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$610
Viewing 1-25 of 33 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).