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GLP2R

glucagon-like peptide 2 receptor

GLP2R, a Glucagon Receptor, is closely related to the Glucagon Receptor and to the GLP1 Receptor. The glucagon-like peptides (GLP-1 and GLP-2) are proglucagon-derived peptides cosecreted from gut endocrine cells in response to nutrient ingestion. The actions of GLP-2 are mediated by the GLP-2 receptor expressed on subsets of enteric nerves and enteroendocrine cells in the stomach and small and large intestine. Activation of GLP2R signaling promotes expansion of the mucosal epithelium indirectly via activation of growth and anti-apoptotic pathways. GLP2R, through its ligand glucagon-like peptide 2 (GLP2), has been shown to prevent intestinal hypoplasia resulting from total parenteral nutrition.

Gene Name: glucagon-like peptide 2 receptor
Family/Subfamily: GPCR , Glucagon
Synonyms: GLP2R, GLP-2-R, GLP-2 receptor, GLP-2R, Glp2 receptor
Target Sequences: NM_004246 NP_004237.1 O95838

Publications (6)

1
GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow. Guan X, Karpen HE, Stephens J, Bukowski JT, Niu S, Zhang G, Stoll B, Finegold MJ, Holst JJ, Hadsell D, Hadsell DL, Nichols BL, Burrin DG. Gastroenterology. 2006 130:150-64. (ICC, WB, IHC-P, Compet; Monkey, Pig) [PubMed:16401478] Related Antibodies: LS-A1312.
2
Glucagon-like peptide-2 modulates neurally evoked mucosal chloride secretion in guinea pig small intestine in vitro. Baldassano S, Liu S, Qu MH, Mul F, Wood JD. American journal of physiology. Gastrointestinal and liver physiology. 2009 297:G800-5. (IHC; Guinea pig) [Full Text Article] [PubMed:19628655] [PMC:PMC2763802] Related Antibodies: LS-A1312.
3
Influence of Cane Molasses Inclusion to Dairy Cow Diets during the Transition Period on Rumen Epithelial Development. William F Miller, Evan C Titgemeyer, Tiruvoor G Nagaraja, Daniel H M Watanabe, Luana D Felizari, Danilo D Millen, Zachary K Smith, Bradley J Johnson. Animals: an open access journal from MDPI. 2021 April;11: [Full Text Article] [PubMed:33923260] [PMC:PMC8145355] Related Antibodies: LS-A1312.
4
GLP-2 Is Locally Produced From Human Islets and Balances Inflammation Through an Inter-Islet-Immune Cell Crosstalk. Wei He, Osmond D Rebello, Antonia Henne, Fabian Nikolka, Thomas Klein, Kathrin Maedler. Frontiers in endocrinology. 2021 July;12:697120. [Full Text Article] [PubMed:34290670] [PMC:PMC8287580] Related Antibodies: LS-A1312.
5
Acute effects of the glucagon-like peptide 2 analogue, teduglutide, on intestinal adaptation in short bowel syndrome. Thymann T, Stoll B, Mecklenburg L, Burrin DG, Vegge A, Qvist N, Eriksen T, Jeppesen PB, Sangild PT. Journal of pediatric gastroenterology and nutrition. 2014 Jun;58:694-702. [Full Text Article] [PubMed:24399211] Related Antibodies: LS-A1312.
6
Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration. El-Jamal N, Erdual E, Neunlist M, Koriche D, Dubuquoy C, Maggiotto F, Chevalier J, Berrebi D, Dubuquoy L, Boulanger E, Cortot A, Desreumaux P. American journal of physiology. Gastrointestinal and liver physiology. Aug;307:G274-85. [Full Text Article] [PubMed:24875097] Related Antibodies: LS-A1312.
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Antibodies (30)
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Over-Expression Lysate (1)
Primary (30)
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GLP2R (37)
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rabbit (23)
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Alzheimer's Disease (37)
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monoclonal mc (7)
polyclonal pc (23)
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GLP2R Antibody - Brain, hippocampus CA2
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Neuroscience
GLP2R Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Guinea pig, Human, Monkey
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$440
GLP2R Antibody - Anti-GLP2R antibody IHC of human small intestine, intraepithelial neuroendocrine cells and enterocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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GLP2R Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
GLP2R Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
GLP2R Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
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GLP2R Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, ICC
Unconjugated
100 µg/$896
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GLP2R Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$414
GLP2R Antibody - Anti-GLP2R antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
GLP2R Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
GLP2R Antibody - Western blot analysis of extracts of various cell lines.
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GLP2R Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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GLP2R Mouse anti-Human Monoclonal (aa69-178) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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GLP2R Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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GLP2R Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
GLP2R Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
GLP2R Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
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GLP2R Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
GLP2R Antibody - Western blot analysis GLP2R using 293 whole cells lysates
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GLP2R Rabbit anti-Human Polyclonal Antibody
Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GLP2R Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
GLP2R Antibody - Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution 1:100
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GLP2R Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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GLP2R Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
Select
GLP2R Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
Select
GLP2R Rabbit anti-Human Polyclonal (aa220-248) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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GLP2R Rabbit anti-Human Polyclonal (aa220-248) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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GLP2R Rabbit anti-Human Polyclonal (aa220-248) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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GLP2R Rabbit anti-Human Polyclonal (aa220-248) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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GLP2R Rabbit anti-Human Polyclonal (aa220-248) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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GLP2R Rabbit anti-Human Polyclonal (aa220-248) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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GLP2R Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 37 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).