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GNAQ

guanine nucleotide binding protein (G protein), q polypeptide

Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.

Gene Name: guanine nucleotide binding protein (G protein), q polypeptide
Synonyms: GNAQ, G-ALPHA-q, GAQ
Target Sequences: NM_002072 NP_002063.2 P50148

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Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
GNAQ (7)
No (7)
10His, N-terminus + Myc, C-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (3)
GNAQ Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
GNAQ Protein - Purified recombinant protein GNAQ was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42 kDa
20 µg/$1,107
GNAQ Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GNAQ Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
42 kDa
20 µg/$150
GNAQ Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42 kDa
100 µg/$494
GNAQ Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
49.2 kDa
20 µg/$405; 1 mg/$1,679; 100 µg/$598
GNAQ Protein - 12.5% SDS-PAGE of human GNAQ stained with Coomassie Blue
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Wheat Germ Extract
GST
65.23 kDa
10 µg/$479; 25 µg/$670
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).