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GPR161

G protein-coupled receptor 161

Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown.

Gene Name: G protein-coupled receptor 161
Family/Subfamily: GPCR , Orphan-U
Synonyms: GPR161, G-protein coupled receptor 161, G protein-coupled receptor 161, G-protein coupled receptor RE2, RE2
Target Sequences: NM_007369 NP_722561.1 Q8N6U8

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Products
Antibodies (34)
Primary (34)
GPR161 (34)
Human (34)
Mouse (11)
Bat (3)
Bovine (10)
Chimpanzee (9)
Dog (4)
Gibbon (12)
Guinea pig (9)
Hamster (1)
Horse (4)
Monkey (11)
Pig (10)
Rabbit (4)
IHC (23)
IHC-P (15)
WB (30)
ELISA (14)
ICC (1)
Peptide-ELISA (1)
rabbit (28)
mouse (6)
Product Group
GPCR Database Antibodies (3)
IHCPlus (1)
PathPlus Neuro (2)
IgG (24)
IgG2a,k (6)
monoclonal mc (6)
polyclonal pc (28)
APC Conjugated (1)
Biotin Conjugated (6)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (1)
Unconjugated (14)
C-Terminus (5)
N-Terminus (5)
aa201-250 (4)
aa360-409 (4)
Cytoplasmic Domain (1)
aa362-461 (1)
No (34)
GPR161 Antibody - Anti-GPR161 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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GPR161 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ICC, IHC, IHC-P
Unconjugated
50 µg/$460
GPR161 Antibody - Anti-GPR161 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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GPR161 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Dog, Bovine, Pig, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
GPR161 Antibody - GPR161 antibody ARP42712_T100-CAI22622-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
GPR161 Antibody - GPR161 antibody ARP42712_T100-CAI22622-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Gibbon, Human, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
GPR161 Antibody - GPR161 antibody ARP42712_T100-CAI22622-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Gibbon, Human, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
GPR161 Antibody - GPR161 antibody ARP42712_T100-CAI22622-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Gibbon, Human, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
GPR161 Antibody - Anti-GPR161 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 2-3 ug/ml.
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GPR161 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Hamster, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
GPR161 Antibody - GPR161 antibody ARP42353_T100-NP_722561-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
GPR161 Antibody - GPR161 antibody ARP42353_T100-NP_722561-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Guinea pig, Pig, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
GPR161 Antibody - GPR161 antibody ARP42353_T100-NP_722561-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Guinea pig, Pig, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
GPR161 Antibody - GPR161 antibody ARP42353_T100-NP_722561-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Guinea pig, Pig, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
GPR161 Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using GPR161 Polyclonal Antibody at dilution of 1:40(×200)
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GPR161 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
GPR161 Antibody - Immunofluorescent analysis of Hela cells using GPR161 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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GPR161 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
GPR161 Antibody - Western blot of 60S ribosomal protein L17 antibody at 2 ug/ml + EC109whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 58 kDa. Observed band size: 30 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
GPR161 Antibody - Western blot of 60S ribosomal protein L17 antibody at 2 ug/ml + EC109whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 58 kDa. Observed band size: 30 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
GPR161 Antibody - Western blot of 60S ribosomal protein L17 antibody at 2 ug/ml + EC109whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 58 kDa. Observed band size: 30 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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GPR161 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
GPR161 Antibody - GPR161 antibody ARP42354_P050-NP_031395-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (aa201-250) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
GPR161 Antibody - GPR161 antibody ARP42354_P050-NP_031395-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (aa201-250) (HRP) Antibody
Mouse, Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
GPR161 Antibody - GPR161 antibody ARP42354_P050-NP_031395-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GPR161 Rabbit anti-Human Polyclonal (aa201-250) (Biotin) Antibody
Mouse, Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
GPR161 Antibody - GPR161 antibody ARP42354_P050-NP_031395-GPR161(G protein-coupled receptor 161) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR161 Rabbit anti-Human Polyclonal (aa201-250) (FITC) Antibody
Mouse, Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
GPR161 Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GPR161 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GPR161 Mouse anti-Human Monoclonal (aa362-461) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
GPR161 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer tissue  using GPR161 Polyclonal Antibody at dilution of 1:40(×200)
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GPR161 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
GPR161 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).