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Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system.
|Gene Name:||G protein-coupled receptor 84|
|Family/Subfamily:||GPCR , Orphan-A|
|Synonyms:||GPR84, EX33, GPCR4, G-protein coupled receptor 84, G protein-coupled receptor 84|
|Target Sequences:||NM_020370 NP_065103.1 Q9NQS5|
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