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HBB / Hemoglobin Beta

hemoglobin, beta

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin that sickles causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene Name: hemoglobin, beta
Synonyms: HBB, CD113t-C, Hemoglobin beta, Hemoglobin beta chain, Hemoglobin subunit beta, Beta globin chain, Beta-globin, Hemoglobin, beta
Target Sequences: NM_000518 NP_000509.1 P68871

Publications (1)

1
Iron imaging in myocardial infarction reperfusion injury. Brianna F Moon, Srikant Kamesh Iyer, Eileen Hwuang, Michael P Solomon, Anya T Hall, Rishabh Kumar, Nicholas J Josselyn, Elizabeth M Higbee-Dempsey, Andrew Tsourkas, Akito Imai, Keitaro Okamoto, Yoshiaki Saito, James J Pilla, Joseph H Gorman rd, Robert C Gorman, Cory Tschabrunn, Samuel J Keeney, Estibaliz Castillero, Giovanni Ferrari, Steffen Jockusch, Felix W Wehrli, Haochang Shou, Victor A Ferrari, Yuchi Han, Avanti Gulhane, Harold Litt, William Matthai, Walter R Witschey. Nature communications. 2020 June;11:3273. [Full Text Article] [PubMed:32601301] [PMC:PMC7324567] Related Antibodies: LS-C755633.

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Proteins (12)
Native (1)
Over-Expression Lysate (3)
Recombinant (8)
HBB / Hemoglobin Beta (12)
No (12)
GST, N-terminus (1)
His, N-Terminal (1)
His-S (2)
His-T7 (3)
Myc-DDK (Flag) (4)
Bovine (1)
Chicken (1)
Horse (1)
Human (4)
Mouse (1)
Sheep (2)
293T Cells (1)
E. coli (6)
HEK 293 Cells (3)
Sheep (1)
Wheat Germ Extract (1)
HBB / Hemoglobin Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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Human HBB / Hemoglobin Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76406
293T Cells
Myc-DDK (Flag)
15.8 kDa
20 µg/$150
HBB / Hemoglobin Beta Protein - Recombinant Hemoglobin Beta By SDS-PAGE
Select
Mouse HBB / Hemoglobin Beta Protein (Recombinant His, N-Terminal) (aa1-147) - LS-G15159
E. coli
His, N-Terminal
21.5 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
HBB / Hemoglobin Beta Protein - Recombinant Hemoglobin Beta By SDS-PAGE
Select
Human HBB / Hemoglobin Beta Protein (Recombinant His-T7) - LS-G25214
E. coli
His-T7
20.7 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
HBB / Hemoglobin Beta Protein - Purified recombinant protein HBB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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Human HBB / Hemoglobin Beta Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65853
HEK 293 Cells
Myc-DDK (Flag)
15.8 kDa
20 µg/$1,107
HBB / Hemoglobin Beta Protein - Recombinant Hemoglobin Beta By SDS-PAGE
Select
Bovine HBB / Hemoglobin Beta Protein (Recombinant His-T7) (aa1-145) - LS-G25212
E. coli
His-T7
20.6 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
HBB / Hemoglobin Beta Protein - Recombinant Hemoglobin Beta By SDS-PAGE
Select
Horse HBB / Hemoglobin Beta Protein (Recombinant His-T7) (aa1-147) - LS-G25213
E. coli
His-T7
20.0 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
HBB / Hemoglobin Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HBB / Hemoglobin Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99060
HEK 293 Cells
Myc-DDK (Flag)
15.9 kDa
100 µg/$494
HBB / Hemoglobin Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HBB / Hemoglobin Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99059
HEK 293 Cells
Myc-DDK (Flag)
15.8 kDa
100 µg/$494
Select
Sheep HBB / Hemoglobin Beta Protein (Native) - LS-G23800
Sheep
None
166.0 kDa
10 µg/$259; 50 µg/$331; 200 µg/$602; 100 µg/$482; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,648
HBB / Hemoglobin Beta Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Human HBB / Hemoglobin Beta Protein (Recombinant GST, N-terminus) (aa38-147) - LS-G58818
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HBB / Hemoglobin Beta Protein - Recombinant Hemoglobin Beta By SDS-PAGE
Select
Chicken HBB / Hemoglobin Beta Protein (Recombinant His-S) (aa1-147) - LS-G15160
E. coli
His-S
22.2 kDa
10 µg/$274; 50 µg/$400; 100 µg/$637; 200 µg/$797; 1 mg/$1,870; 500 µg/$1,424; 5 mg/$2,832; 2 mg/$2,053
HBB / Hemoglobin Beta Protein - Recombinant Hemoglobin Beta By SDS-PAGE
Select
Sheep HBB / Hemoglobin Beta Protein (Recombinant His-S) (aa1-145) - LS-G15163
E. coli
His-S
22.6 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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