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HCAR3 / GPR109B / HM74

hydroxycarboxylic acid receptor 3

Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.

Gene Name:	hydroxycarboxylic acid receptor 3
Family/Subfamily:	GPCR , Nicotinic Acid
Synonyms:	HCAR3, GPR109B, GTP-binding protein, NIACR2, HM74, HM74b, Nicotinic acid receptor 2, Putative chemokine receptor, Niacin receptor 2, Puma-g, HCA3, PUMAG
Target Sequences:	NM_006018 NP_006009.2 P49019

HCAR3 / GPR109B / HM74 Protein - 12.5% SDS-PAGE of human GPR109B stained with Coomassie Blue

Human HCAR3 / GPR109B / HM74 Protein (Recombinant GST) (Full Length) - LS-G31361

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

70.9 kDa

Price:

2 µg/$439

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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