Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
Gene Name: | Major Histocompatibility Complex, Class I, G Heavy Chain |
Synonyms: | HLA-G, HLAG, HLA-6.0, MHC class I antigen G, HLA G antigen |
Target Sequences: | NM_002127 NP_002118.1 P17693 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.