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HPN / TMPRSS1 / Hepsin

hepsin

HPN / TMPRSS1 / Hepsin is a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants.

Gene Name: hepsin
Family/Subfamily: Protease , Serine S1
Synonyms: HPN, Hepsin, TMPRSS1, Serine protease hepsin
Target Sequences: NM_002151 NP_002142.1 P05981

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Products
Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
HPN / TMPRSS1 / Hepsin (6)
No (6)
GST (1)
GST, N-terminus + His, C-terminus (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
HPN / TMPRSS1 / Hepsin Protein - 12.5% SDS-PAGE of human HPN stained with Coomassie Blue
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Wheat Germ Extract
GST
67.43 kDa
10 µg/$479; 25 µg/$670
HPN / TMPRSS1 / Hepsin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
44.8 kDa
100 µg/$710
HPN / TMPRSS1 / Hepsin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
44.8 kDa
20 µg/$150
HPN / TMPRSS1 / Hepsin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
44.8 kDa
20 µg/$215
HPN / TMPRSS1 / Hepsin Protein
Select
E. coli
GST, N-terminus + His, C-terminus
72.8 kDa
50 µg/$419
HPN / TMPRSS1 / Hepsin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
44.8 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).