HTR6 / 5-HT6 Receptor

5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled

5-HT6, a Serotonin Receptor, appears to regulate cholinergic neurotransmission in the brain rather than the expected interaction as a modulator of dopaminergic transmission. This interaction predicts a possible role for 5-HT6 Receptor antagonists in the treatment of learning and memory disorders. The 5-HT6 Receptor is abundant in limbic areas, which participate in the control of mood and emotion. Some antidepressants and antipsychotics are potent 5-HT6 Receptor antagonists, making this gene valuable for the pharmaceutical industry. 5-HT6 may be involved in the pathogenesis of mood disorders, schizophrenia, in Alzheimer's disease. A splice variant that has a 289bp deletion in the transmembrane region IV and the third intracellular loop has been isolated.

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Proteins (2)

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Over-Expression Lysate (2)

Target

HTR6 / 5-HT6 Receptor (2)

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No (2)

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Myc-DDK (Flag) (2)

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Human (1)

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293T Cells (1)

HEK 293 Cells (1)

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HTR6 / 5-HT6 Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99192

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

100 µg/$494

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Human HTR6 / 5-HT6 Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74143

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

20 µg/$150

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