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HTR7 / 5HT7 Receptor

5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled

5-HT7 Receptor (HTR7 )is a serotonin receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. HTR7 has been implicated in depression, autistic, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
Family/Subfamily: GPCR , Serotonin
Synonyms: HTR7, 5-HT7, 5-HT7 receptor, 5-HT-7, 5-hydroxytryptamine 7 receptor, 5HT7, 5-HT-X, 5-hydroxytryptamine receptor 7, 5HT7 Receptor, HT7, Serotonin 5-HT7 receptor, Serotonin receptor 7
Target Sequences: NM_019859 NP_062873.1 P34969

Publications (4)

1
5-HT is a potent relaxant in rat superior mesenteric veins. Watts SW, Darios ES, Seitz BM, Thompson JM. Pharmacology research & perspectives. 2015 3:e00103. (IHC; Rat) [Full Text Article] [PubMed:25692021] [PMC:PMC4317234]
2
Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia. Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A F MacLeod, Hans G Drexler. PloS one. 2020 October;15:e0240120. [Full Text Article] [PubMed:33048949] [PMC:PMC7553312] Related Antibodies: LS-C358892.
3
Expression of 5-Hydroxytryptamine Receptors in Human Urinary Bladders with Benign Prostatic Hyperplasia. Tetsuya Imamura, Osamu Ishizuka , Teruyuki Ogawa, Tomonori Minagawa, Masakuni Ishikawa, Shiro Hiragata, Hitoshi Yokoyama, Masaki Nakazawa, Yoshiki Kurizaki, Osamu Nishizawa. The Breast : official journal of the European Society of Mastology. 2015 Oct;;32:29-37. [Full Text Article] [PubMed:26391373] Related Antibodies: LS-A6673.
4
Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome. De Filippis B, Nativio P, Fabbri A, Ricceri L, Adriani W, Lacivita E, Leopoldo M, Passarelli F, Fuso A, Laviola G. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2014 Oct;39:2506-18. [Full Text Article] [PubMed:24809912] [PMC:PMC4207333] Related Antibodies: LS-C39057.
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HTR7 / 5HT7 Receptor (45)
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HTR7 / 5HT7 Receptor Antibody - Anti-5HT7 Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
HTR7 / 5HT7 Receptor Antibody - Anti-5HT7 Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
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Fast Shipping
HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
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HTR7 / 5HT7 Receptor Rabbit anti-Rat Polyclonal (aa8-23) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100 µl/$856
HTR7 / 5HT7 Receptor Antibody - Western blot analysis of 5-HT7 expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
HTR7 / 5HT7 Receptor Antibody - Anti-HTR7 / 5-HT7 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
HTR7 / 5HT7 Receptor Antibody - Anti-HT7 / 5-HT7 antibody IHC of human brain, cortex, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 19 ug/ml.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IF, IHC, IHC-P
Unconjugated
50 µg/$440
HTR7 / 5HT7 Receptor Antibody - Anti-5HT7 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
HTR7 / 5HT7 Receptor Antibody - Western blot of 5-HT7R in human brain tissue lysate with anti-5-HT7R pcAb. A protein band of approximate molecular weight of 50 kD was detected.
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HTR7 / 5HT7 Receptor Rabbit anti-Rat Polyclonal (aa13-28) Antibody
Mouse, Dog, Rat, Human
WB
Unconjugated
0.1 mg/$386
HTR7 / 5HT7 Receptor Antibody - Anti-HTR7 / 5-HT7 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
HTR7 / 5HT7 Receptor Antibody - Peptide - + Immunofluorescence analysis of COS-7 cells, using HTR7 antibody.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
100 µg/$357
HTR7 / 5HT7 Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$669
HTR7 / 5HT7 Receptor Antibody - Immunohistochemistry image of paraffin-embedded human endometrial cancer at a dilution of 1:100
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (370-450 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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HTR7 / 5HT7 Receptor Rabbit-New Zealand White anti-Human Polyclonal (aa150-200) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$393
HTR7 / 5HT7 Receptor Antibody - Immunofluorescence analysis of COS7 cells, using HTR7 Antibody. The picture on the right is blocked with the synthesized peptide.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa391-440) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HTR7 / 5HT7 Receptor Antibody - HTR7 antibody (1 ug/ml) staining of KELLY lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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HTR7 / 5HT7 Receptor Goat anti-Human Polyclonal (aa433-445) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa47-96) Antibody
Human
WB
Unconjugated
100 µl/$397
Viewing 1-25 of 45 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).