IDH1 / IDH

isocitrate dehydrogenase 1 (NADP+), soluble

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

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Products

ELISA Kits (14)

Type

Competitive EIA (2)

Custom (4)

Development Kit (1)

Sandwich (6)

Sandwich CLIA (1)

Target

IDH1 / IDH (14)

Reactivity

Human (7)

Mouse (1)

Rat (4)

Pig (1)

Product Group

DevKit DuoPlus (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (12)

Antibody Pair and Standard (1)

Publications

No (14)

Sample Type

Cell Culture Supernatants (4)

Cell Lysates (4)

Plasma (10)

Serum (10)

Tissue Homogenates (6)

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Human IDH1 / IDH (CLIA) ELISA Kit - LS-F26596

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.69 - 500 ng/ml

Detection:

Chemiluminescent

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$851

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Rat IDH1 / IDH (Sandwich ELISA) ELISA Kit - LS-F7777

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

3.13 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Human IDH1 / IDH (Sandwich ELISA) ELISA Kit - LS-F7198

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$730

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Human IDH1 / IDH (Sandwich ELISA) ELISA Kit - LS-F13239

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse IDH1 / IDH (Custom ELISA) ELISA Kit - LS-F16269

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Pig IDH1 / IDH (Custom ELISA) ELISA Kit - LS-F16270

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Bovine IDH1 / IDH (Custom ELISA) ELISA Kit - LS-F16271

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Rat IDH1 / IDH (Custom ELISA) ELISA Kit - LS-F16272

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human IDH1 / IDH (Sandwich ELISA) ELISA Kit - LS-F33665

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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DevKit DuoPlus Human IDH1 / IDH ELISA Development Kit - LS-F71969

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,276; 1000 Wells/$1,903

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Rat IDH1 / IDH (Sandwich ELISA) ELISA Kit - LS-F22368

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human IDH1 / IDH (Sandwich ELISA) ELISA Kit - LS-F25126

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.125 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$855

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Human IDH1 / IDH (Competitive EIA) ELISA Kit - LS-F27723

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

10 - 250 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Rat IDH1 / IDH (Competitive EIA) ELISA Kit - LS-F28001

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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