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IGF1

insulin-like growth factor 1 (somatomedin C)

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.

Gene Name: insulin-like growth factor 1 (somatomedin C)
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IGF1, IGF-IA, IGF-IB, IGFI, IBP1, IGF-I, Insulin-like growth factor 1, Insulin-like growth factor I, Insulin-like growth factor IA, Insulin-like growth factor IB, Mechano growth factor, Somatomedin-C, IGF1A, MGF
Target Sequences: NM_000618 NP_000609.1 P05019

Publications (5)

1
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance. Somasundaram R, Zhang G, Fukunaga-Kalabis M, Perego M, Krepler C, Xu X, Wagner C, Hristova D, Zhang J, Tian T, Wei Z, Liu Q, Garg K, Griss J, Hards R, Maurer M, Hafner C, Mayerhöfer M, Karanikas G, Jalili A, Bauer-Pohl V, Weihsengruber F, Rappersberger K, Koller J, Lang R, Hudgens C, Chen G, Tetzlaff M, Wu L, Frederick DT, Scolyer RA, Long GV, Damle M, Ellingsworth C, Grinman L, Choi H, Gavin BJ, Dunagin M, Raj A, Scholler N, Gross L, Beqiri M, Bennett K, Watson I, Schaider H, et al. Nature communications. 2017 8:607. (WB; Human) [Full Text Article] [PubMed:28928360] Related Antibodies: LS-C7504.
2
Cytokine Mixtures Mimicking Secretomes From Mesenchymal Stem Cells Improve Medication-Related Osteonecrosis of the Jaw in a Rat Model. Ogata K, Matsumura M, Moriyama M, Katagiri W, Hibi H, Nakamura S. JBMR plus. 2017 September;2:69-80. [Full Text Article] [PubMed:30283893] [PMC:PMC6124208] Related Antibodies: LS-C36891.
3
A defined mix of cytokines mimics conditioned medium from cultures of bone marrow-derived mesenchymal stem cells and elicits bone regeneration. Katagiri W, Sakaguchi K, Kawai T, Wakayama Y, Osugi M, Hibi H. Cell proliferation. 2017 June;50: [Full Text Article] [PubMed:28133828] Related Antibodies: LS-C36891.
4
Biomaterial and implant induced ossification: in vitro and in vivo findings. Pekka K Vallittu, Jussi P Posti, Jaakko M Piitulainen, Willy Serlo, Jorma A Määttä, Terhi J Heino, Stefania Pagliari, Stina M Syrjänen, Giancarlo Forte. Journal of tissue engineering and regenerative medicine. 2020 August;14:1157-1168. [Full Text Article] [PubMed:32415757] [PMC:PMC7496445] Related Antibodies: LS-C388624.
5
Multiple protein biomarker assessment for recombinant bovine somatotropin (rbST) abuse in cattle. Ludwig SK, Smits NG, van der Veer G, Bremer MG, Nielen MW. PloS one. 2013 7:e52917. (Flo; Human) [Full Text Article] [PubMed:23300820] [PMC:PMC3531382] Related Antibodies: LS-C392250.
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IGF1 (67)
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IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
IGF1 ELISA Kit
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Sandwich
96-Well Microplate
Rabbit
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Canine
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$811
IGF1 ELISA Kit
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Sandwich
96-Well Microplate
Bovine
1.23 - 300 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$610
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$715
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$610
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$715
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
IGF1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
2.743 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$426
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IGF1 ELISA Kit
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Competitive EIA
12 x 8-Well Microstrips
Deer
1 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$869
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.19 - 12 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$610
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$779
IGF1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.19 - 12 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$671
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$779
IGF1 ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$713
IGF1 ELISA Kit
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Sandwich
96-Well Microplate
Pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
IGF1 ELISA Kit
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Sandwich
96-Well Microplate
Chicken
18.75 - 1200 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
IGF1 ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Mouse
27.4 - 20000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$871
IGF1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
IGF1 ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Mouse
62 - 6000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$414
IGF1 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.123 - 30 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
IGF1 ELISA Kit
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Sandwich
96-Well Strip Plate
Goat
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).