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IGF2
insulin-like growth factor 2 (somatomedin A)
The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
| Gene Name: | insulin-like growth factor 2 (somatomedin A) |
| Family/Subfamily: | Hormone , not assigned-Hormone |
| Synonyms: | IGF2, C11orf43, IGF-II, PP9974, Somatomedin-A |
| Target Sequences: | NM_000612 NP_000603.1 P01344 |
Publications (4)
1
Maternal supplementation of energy and protein, but not methionine hydroxy analog, enhanced postnatal growth and response to vaccination in Bos indicus-influenced beef offspring. Philipe Moriel, Marcelo Vedovatto, Elizabeth A Palmer, Rhaiza A Oliveira, Hiran Marcelo Silva, Juliana Ranches, Joao M B Vendramini. Journal of animal science. 2020 May;98: [Full Text Article]
[PubMed:32309862]
[PMC:PMC7228674]
2
Monensin supplementation during late gestation of beef cows alters maternal plasma concentrations of insulin-like growth factors 1 and 2 and enhances offspring preweaning growth. Marcelo Vedovatto, Vinicius Izquierdo, Elizabeth Palmer, Rhaiza A Oliveira, Hiran M Silva, João M B Vendramini, Philipe Moriel. Translational animal science. 2022 July;6:txac105. [Full Text Article]
[PubMed:36046092]
[PMC:PMC9423031]
3
Frequency of maternal supplementation of energy and protein during late gestation modulates preweaning growth of their beef offspring. Vinicius Izquierdo, Marcelo Vedovatto, Elizabeth A Palmer, Rhaiza A Oliveira, Hiran M Silva, João M B Vendramini, Philipe Moriel. Translational animal science. 2022 July;6:txac110. [Full Text Article]
[PubMed:36090697]
[PMC:PMC9449678]
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Cancer
IGF2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$485
Cancer
IGF2 Goat anti-Human Polyclonal (aa81-93) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Human, Monkey
IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
IGF2 Rabbit anti-Human Polyclonal (aa39-68) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$393
Sandwich
96-Well Microplate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
E. coli
His
9.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
Competitive EIA
96-Well Strip Plate
Bovine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Bovine
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$822
IGF2 Mouse anti-Human Monoclonal (8H1) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$459
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$764
IGF2 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$842
Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$782
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IGF2 Mouse anti-Human Monoclonal (Amino Acid: 25-180) (8H1) Antibody
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µg/$503
IGF2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, Func, Neut, WB
Biotin Conjugated
25 µg/$394; 50 µg/$469
IGF2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
IGF2 Rabbit anti-Human Polyclonal Antibody
Human
IHC
Unconjugated
50 µl/$717
IGF2 Rabbit anti-Rat Polyclonal Antibody
Rat
IHC, IHC-Fr
Unconjugated
100 µl/$587
IGF2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
20 µl/$275; 100 µl/$389
IGF2 Rabbit anti-Mouse Monoclonal (Preservative Free) (110) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
IGF2 Mouse anti-Human Monoclonal (aa39-68) Antibody
Human
WB
Unconjugated
0.1 ml/$393
IGF2 Rabbit anti-Human Polyclonal (aa39-68) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
IGF2 Rabbit anti-Human Polyclonal (aa39-68) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
IGF2 Rabbit anti-Human Polyclonal (aa39-68) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
IGF2 Rabbit anti-Rat Polyclonal (aa25-91) Antibody
Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
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