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IL11RA
interleukin 11 receptor, alpha
Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.
| Gene Name: | interleukin 11 receptor, alpha |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL11RA, CRSDA, IL-11R-alpha, IL-11R subunit alpha, Interleukin 11 receptor, alpha, IL-11 receptor subunit alpha, IL-11RA |
| Target Sequences: | NM_004512 NP_004503.1 Q14626 |
Publications (1)
1
IL-11 is a crucial determinant of cardiovascular fibrosis. Schafer S, Viswanathan S, Widjaja AA, Lim WW, Moreno-Moral A, DeLaughter DM, Ng B, Patone G, Chow K, Khin E, Tan J, Chothani SP, Ye L, Rackham OJL, Ko NSJ, Sahib NE, Pua CJ, Zhen NTG, Xie C, Wang M, Maatz H, Lim S, Saar K, Blachut S, Petretto E, Schmidt S, Putoczki T, Guimarães-Camboa N, Wakimoto H, van Heesch S, Sigmundsson K, Lim SL, Soon JL, Chao VTT, Chua YL, Tan TE, Evans SM, Loh YJ, Jamal MH, Ong KK, Chua KC, Ong BH, Chakaramakkil MJ, Seidman JG, Seidman CE, Hubner N, Sin KYK, Cook SA. Nature. 2017 December;552:110-115. [Full Text Article]
[PubMed:29160304]
[PMC:PMC5807082]
☰ Filters
Products
Proteins
(14)
Type
Over-Expression Lysate
(6)
Recombinant
(8)
Target
IL11RA
(14)
Publications
No
(14)
Tag
6His, C-terminus
(1)
GST
(1)
His
(3)
His,C-terminus
(2)
His-T7
(1)
Myc-DDK (Flag)
(6)
Species
Human
(6)
Mouse
(4)
Rat
(1)
Source
293T Cells
(3)
E. coli
(4)
HEK 293 Cells
(5)
Human
(1)
Wheat Germ Extract
(1)
Purification
Purified
(3)
Low Endotoxin Level
Low endotoxin level
(3)
E. coli
His-T7
41.9 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
E. coli
His
18.9 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
E. coli
His
19.1 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
E. coli
His
16.8 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Wheat Germ Extract
GST
72.16 kDa
10 µg/$479; 25 µg/$670
293T Cells
Myc-DDK (Flag)
45.22 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
39.7 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
45.22 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
45.22 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
39.7 kDa
100 µg/$494
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.5 kDa
10 µg/$239; 50 µg/$294
HEK 293 Cells
Myc-DDK (Flag)
45.22 kDa
100 µg/$494
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
39.2 kDa
100 µg/$793; 1 mg/$4,191
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.6 kDa
100 µg/$721
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product results
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