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Vector Laboratories, Inc.
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IL15

interleukin 15

IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.

Gene Name: interleukin 15
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL15, Interleukin-15, IL-15, Interleukin 15
Target Sequences: NM_000585 NP_000576.1 P40933

Publications (1)

1
Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression. Ralph Francescone , Débora Barbosa Vendramini-Costa , Janusz Franco-Barraza, Jessica Wagner, Alexander Muir, Allison N Lau, Linara Gabitova, Tatiana Pazina, Sapna Gupta, Tiffany Luong, Dustin Rollins, Ruchi Malik, Roshan J Thapa, Diana Restifo, Yan Zhou, Kathy Q Cai, Harvey H Hensley, Yinfei Tan, Warren D Kruger, Karthik Devarajan, Siddharth Balachandran, Andres J Klein-Szanto, Huamin Wang, Wafik S El-Deiry, Matthew G Vander Heiden, Suraj Peri, Kerry S Campbell, Igor Astsaturov, Edna Cukierman. Cancer discovery. 2021 February;11:446-479. [Full Text Article] [PubMed:33127842] [PMC:PMC7858242] Related Antibodies: LS-B10080.

☰ Filters
Products
Proteins (37)
Over-Expression Lysate (2)
Recombinant (35)
IL15 (37)
Animal-free (1)
No (37)
6His, N-terminus (1)
GST (2)
GST, N-terminus (1)
His (9)
His, N-Terminal (1)
His-S (1)
Human IgG1 Fc (1)
Mouse IgG2 Fc (1)
Myc-DDK (Flag) (3)
Bovine (2)
Guinea pig (1)
Human (21)
Mouse (5)
Rabbit (1)
Rat (2)
Rhesus monkey (1)
Sheep (1)
293T Cells (1)
CHO Cells (2)
E. coli (25)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Yeast (2)
Purified (14)
Low endotoxin level (17)
Biologically active (14)
Animal-free (1)
IL15 Protein
Select
Yeast
6His, N-terminus
14.9 kD
100 µg/$679; 20 µg/$429; 1 mg/$1,973
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
12.9 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$281; 10 µg/$369
IL15 Protein
Select
E. coli
His
14.6 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
13.5 kDa
2 µg/$268; 10 µg/$349
Select
CHO Cells
Mouse IgG2 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
1 Vial/$512
Select
CHO Cells
Human IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$498
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
13.3 kDa
2 µg/$268; 10 µg/$349
IL15 Protein
Select
E. coli
None
Biologically active
12.9 kDa
10 µg/$388; 100 µg/$1,186; 500 µg/$2,269
IL15 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
IL15 Protein - Purified recombinant protein IL15 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
14.7 kDa
20 µg/$1,107
IL15 Protein - Recombinant Interleukin 15 By SDS-PAGE
Select
E. coli
His
14.8 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
IL15 Protein - Recombinant Interleukin 15 By SDS-PAGE
Select
E. coli
His-S
18.8 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
IL15 Protein - Recombinant Interleukin 15 By SDS-PAGE
Select
E. coli
His
14.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
IL15 Protein - Recombinant Interleukin 15 By SDS-PAGE
Select
E. coli
His
14.2 kDa
10 µg/$300; 50 µg/$562; 100 µg/$897; 200 µg/$1,096; 1 mg/$2,284; 500 µg/$1,796; 5 mg/$3,921; 2 mg/$2,476
IL15 Protein
Select
E. coli
His
14.9 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
Select
E. coli
His
14.7 kDa
10 µg/$304; 50 µg/$587; 100 µg/$940; 200 µg/$1,133; 1 mg/$2,340; 500 µg/$1,848; 5 mg/$4,103; 2 mg/$2,532
Select
E. coli
His
16.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
None
Biologically active
12.9 kDa
10 µg/$476
Select
None
Biologically active
13.3 kDa
10 µg/$476
IL15 Protein - 12.5% SDS-PAGE of human IL15 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
44.5 kDa
10 µg/$479; 25 µg/$670
IL15 Protein - 12.5% SDS-PAGE of human IL15 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
43.56 kDa
10 µg/$479; 25 µg/$670
IL15 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
14.7 kDa
20 µg/$150
IL15 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
14.7 kDa
100 µg/$494
IL15 Protein - Active Interleukin 15 (IL15) by WB
Select
E. coli
His, N-Terminal
14/16/18kDa
10 µg/$402; 50 µg/$1,002; 200 µg/$1,668; 100 µg/$1,430; 1 mg/$3,201; 500 µg/$2,501; 5 mg/$7,001; 2 mg/$3,735
Viewing 1-25 of 37 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).