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IL18

interleukin 18 (interferon-gamma-inducing factor)

Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.

Gene Name: interleukin 18 (interferon-gamma-inducing factor)
Family/Subfamily: IL-1 , not assigned-IL-1
Synonyms: IL18, IGIF, IL-1g, Interleukin-18, IFN-gamma-inducing factor, IL-1 gamma, IL-18, Iboctadekin, IL1F4, Interleukin-1 gamma
Target Sequences: NM_001562 NP_001553.1 Q14116

Publications (5)

1
USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation. Palazón-Riquelme P, Worboys JD, Green J, Valera A, Martín-Sánchez F, Pellegrini C, Brough D, López-Castejón G. EMBO reports. 2018 October;19:pii e44766. [Full Text Article] [PubMed:30206189] [PMC:PMC6172458] Related Antibodies: LS-C313397.
2
High Levels of IL-18 and IFN-? in Chronically Inflamed Tissue in Chronic Granulomatous Disease. Meda Spaccamela V, Valencia RG, Pastukhov O, Duppenthaler A, Dettmer MS, Erb J, Steiner UC, Hillinger S, Speckmann C, Ehl S, Reichenbach J, Siler U. Frontiers in immunology. 2019 October;10: [Full Text Article] [PubMed:31681257] [PMC:PMC6813411] Related Antibodies: LS-C313164.
3
Mincle/Syk signaling promotes intestinal mucosal inflammation through induction of macrophage pyroptosis in Crohn's disease. Wenbin Gong, Tao Zheng, Guo Kun, Fang Miao, Haohao Xie, Li Weijie, Qinqing Tang, Zhiwu Hong, Huajian Ren, Guosheng Gu, Gefei Wang, Xiuwen Wu, Yun Zhao, Jianan Ren. Journal of Crohn's & colitis. 2020 April; [Full Text Article] [PubMed:32333776] Related Antibodies: LS-C754834.
4
Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro. Anna Gritsenko, Shi Yu, Fatima Martin-Sanchez, Ines Diaz-Del-Olmo, Eva-Maria Nichols, Daniel M Davis, David Brough, Gloria Lopez-Castejon. Frontiers in immunology. 2020 October;11:565924. [Full Text Article] [PubMed:33101286] [PMC:PMC7555430] Related Antibodies: LS-C313397.
5
Melatonin attenuates smoking-induced atherosclerosis by activating the Nrf2 pathway via NLRP3 inflammasomes in endothelial cells. Zhewei Zhao, Xuebin Wang, Rui Zhang, Baitao Ma, Shuai Niu, Xiao Di, Leng Ni, Changwei Liu. Aging. 2021 Apr;13:11363-11380. [Full Text Article] [PubMed:33839695] [PMC:PMC8109127]
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☰ Filters
Antibodies (172)
ELISA Kits (59)
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IL18 (269)
Human (79)
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IL18 Antibody - IL18 antibody. IHC(P): Human Tonsil Tissue.
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IL18 Rabbit anti-Human Polyclonal (aa37-193) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$421
IL18 Antibody
Select
IL18 Mouse anti-Human Monoclonal (50008-2) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$425
IL18 Antibody - IL18 antibody. IHC(P): Human Tonsil Tissue.
Select
IL18 Rabbit anti-Human Polyclonal (aa37-193) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$421
IL18 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Dog
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
IL18 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$776
IL18 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.5 - 75 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$616
IL18 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$744
IL18 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
39 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$649
Select
IL18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
IL18 Antibody - IHC analysis of IL-18 using anti-IL-18 antibody. IL-18 was detected in paraffin-embedded section of mouse intestine tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-IL-18 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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IL18 Rabbit anti-Mouse Polyclonal (aa36-192) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$421
IL18 Antibody - Immunohistochemistry with Rabbit anti-Mouse IL-18 antibody showing IL-18 staining in inflammatory cells of the mucous corium of mouse colon at 20x and 40x. Slide A is a negative control. Slides B and C show staining. Formalin fixed/paraffin embedded sections were subjected to heat induced epitope retrieval (HIER) at pH 6.2 and then incubated with mouse anti-IL-18 antibody at 4.0 µg/ml for 60 minutes. The reaction was developed using MACH 4 universal AP polymer detection system and visualized with WARP RED.
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IL18 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IF, IHC, Neut, WB
Unconjugated
25 µl/$275
IL18 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$806
IL18 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$744
IL18 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL18 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$284; 100 µg/$348
IL18 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL18 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P
FITC Conjugated
50 µg/$284; 100 µg/$348
IL18 Antibody - WB on HeLa cell lysate.
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IL18 Mouse anti-Human Recombinant Monoclonal (IL-18) (125-2H) Antibody
Human
ELISA, IF, IP
Unconjugated
0.2 mg/$474
IL18 Antibody - Western blot.
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IL18 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$433
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IL18 Mouse anti-Pig Monoclonal Antibody
Pig
ELISA, WB
Unconjugated
500 µg/$858
IL18 Antibody
Select
IL18 Mouse anti-Mouse Monoclonal (21A12) Antibody
Mouse, Rat
WB
Unconjugated
100 µg/$430
IL18 Antibody - Western Blot; Sample: Recombinant IL18, Mouse.
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IL18 Rabbit anti-Mouse Polyclonal (aa36-192) Antibody
Mouse
WB
Unconjugated
100 µl/$292; 200 µl/$331; 500 µl/$460; 1 ml/$525
IL18 Antibody - Western Blot; Sample: Recombinant IL18, Mouse.
Select
IL18 Rabbit anti-Mouse Polyclonal (aa36-192) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$299; 200 µl/$343; 500 µl/$486; 1 ml/$557
Select
IL18 Mouse anti-Mouse Recombinant Monoclonal (SAIC-24B-4) Antibody
Mouse, Human
Immuno-MRM
Unconjugated
0.2 mg/$474
IL18 Antibody - Western Blot; Sample: Recombinant protein.
Select
IL18 Rabbit anti-Cow Polyclonal (aa37-193) Antibody
Bovine, Cow
WB
Unconjugated
100 µl/$307; 200 µl/$352; 500 µl/$503; 1 ml/$584
IL18 Antibody
Select
IL18 Rabbit anti-Chicken Polyclonal (aa1-196) Antibody
Chicken
WB
Unconjugated
100 µl/$297; 200 µl/$338; 500 µl/$475; 1 ml/$543
IL18 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$693
Viewing 1-25 of 269 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).