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IL18
interleukin 18 (interferon-gamma-inducing factor)
Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.
| Gene Name: | interleukin 18 (interferon-gamma-inducing factor) |
| Family/Subfamily: | IL-1 , not assigned-IL-1 |
| Synonyms: | IL18, IGIF, IL-1g, Interleukin-18, IFN-gamma-inducing factor, IL-1 gamma, IL-18, Iboctadekin, IL1F4, Interleukin-1 gamma |
| Target Sequences: | NM_001562 NP_001553.1 Q14116 |
Publications (5)
1
USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation. Palazón-Riquelme P, Worboys JD, Green J, Valera A, Martín-Sánchez F, Pellegrini C, Brough D, López-Castejón G. EMBO reports. 2018 October;19:pii e44766. [Full Text Article]
[PubMed:30206189]
[PMC:PMC6172458]
Related Antibodies: LS-C313397.
2
High Levels of IL-18 and IFN-? in Chronically Inflamed Tissue in Chronic Granulomatous Disease. Meda Spaccamela V, Valencia RG, Pastukhov O, Duppenthaler A, Dettmer MS, Erb J, Steiner UC, Hillinger S, Speckmann C, Ehl S, Reichenbach J, Siler U. Frontiers in immunology. 2019 October;10: [Full Text Article]
[PubMed:31681257]
[PMC:PMC6813411]
Related Antibodies: LS-C313164.
3
Mincle/Syk signaling promotes intestinal mucosal inflammation through induction of macrophage pyroptosis in Crohn's disease. Wenbin Gong, Tao Zheng, Guo Kun, Fang Miao, Haohao Xie, Li Weijie, Qinqing Tang, Zhiwu Hong, Huajian Ren, Guosheng Gu, Gefei Wang, Xiuwen Wu, Yun Zhao, Jianan Ren. Journal of Crohn's & colitis. 2020 April; [Full Text Article]
[PubMed:32333776]
Related Antibodies: LS-C754834.
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