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IL23A / IL-23 p19
interleukin 23, alpha subunit p19
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
| Gene Name: | interleukin 23, alpha subunit p19 |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL23A, IL-23 subunit alpha, IL-23A, Interleukin 23 p19 subunit, Interleukin-23 subunit alpha, IL23P19, Interleukin-23 subunit p19, p19, SGRF, IL-23, IL-23 p19, IL-23-A, IL-23p19 |
| Target Sequences: | NM_016584 NP_057668.1 Q9NPF7 |
Publications (4)
1
The involvement of IL-23 and the Th17 pathway in periodontitis. Ohyama H, Kato-Kogoe N, Kuhara A, Nishimura F, Nakasho K, Yamanegi K, Yamada N, Hata M, Yamane J, Terada N. Journal of dental research. 2009 88:633-8.
[PubMed:19605880]
Related Antibodies: LS-B3708.
2
Systemic and local interleukin-17 and linked cytokines associated with Sjgren's syndrome immunopathogenesis. Katsifis GE, Rekka S, Moutsopoulos NM, Pillemer S, Wahl SM. The American journal of pathology. 2009 175:1167-77.
[PubMed:19700754]
[PMC:PMC2731135]
Related Antibodies: LS-B3708.
3
Proteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin. Muehlbauer SM, Lima H, Goldman DL, Jacobson LS, Rivera J, Goldberg MF, Palladino MA, Casadevall A, Brojatsch J. The American journal of pathology. 2010 177:735-43.
[PubMed:20595632]
[PMC:PMC2913046]
Related Antibodies: LS-B3708.
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Neuroscience
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Neuroscience
IL23A / IL-23 p19 Mouse anti-Human Monoclonal (HLT2736) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
Neuroscience
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
IL23A / IL-23 p19 Mouse anti-Human Monoclonal (473P19) Antibody
Human
ELISA, SwELISA, WB
Unconjugated
25 µg/$277; 500 µg/$851
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$393
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
IL23A / IL-23 p19 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Fast Shipping
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
IL23A / IL-23 p19 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$361
Fast Shipping
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
IL23A / IL-23 p19 Rat anti-Human Monoclonal (I 178G) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$281; 100 µg/$323
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Human
IHC, WB
HRP Conjugated
100 µl/$973
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
IHC, WB
Biotin Conjugated
100 µl/$973
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
IHC, WB
FITC Conjugated
100 µl/$973
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Human
IHC, WB
PE Conjugated
100 µl/$973
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
IL23A / IL-23 p19 Mouse anti-Human Recombinant Monoclonal (Preservative Free) (mh066) Antibody
Human
ELISA, Neut
Unconjugated, Preservative Free
200 µg/$361; 500 µg/$436
IL23A / IL-23 p19 Rabbit anti-Mouse Polyclonal (aa29-48) Antibody
Mouse
WB
Unconjugated
10 µg/$318; 100 µg/$470
IL23A / IL-23 p19 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
IL23A / IL-23 p19 Mouse anti-Marmoset Monoclonal Antibody
Marmoset
ELISA
Unconjugated
100 µl/$412
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of 37
product results
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