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IL25 / IL17E

interleukin 25

The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Studies have shown that IL17E binds strongly to IL17RB. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8. Exposure of mice to IL17 resulted in a Th-2 like response characterized by increased serum IgE, IgG1 and IgA levels, blood eosinophilia, increased lymphocytes and neutrophils, and pathological changes in the tissues that included eosinophilic infiltrates, increased mucus production, B-lymphocyte hyperplasia and epithelial cell hyperplasia/hypertrophy.

Gene Name: interleukin 25
Family/Subfamily: Interleukin
Synonyms: IL25, Interleukin 17E, Interleukin 25, Interleukin-25, IL17E, IL-17E, IL-25, Interleukin-17E
Target Sequences: NM_022789 NP_073626.1 Q9H293

Publications (3)

1
Interleukin-25: a cytokine linking eosinophils and adaptive immunity in Churg-Strauss syndrome. Terrier B, Bièche I, Maisonobe T, Laurendeau I, Rosenzwajg M, Kahn JE, Diemert MC, Musset L, Vidaud M, Sène D, Costedoat-Chalumeau N, Le Thi-Huong D, Amoura Z, Klatzmann D, Cacoub P, Saadoun D. Blood. 2010 116:4523-31. (WB; Human) [Full Text Article] [PubMed:20729468] Related Antibodies: LS-B123.
2
Elevations in Th2-initiating cytokines (IL-33, IL-25, TSLP) in lesional skin from Chronic Spontaneous ("Idiopathic") Urticaria. Clark P, Maurer M, Ying S. The British journal of dermatology. Dec; [Full Text Article] [PubMed:25523947] Related Antibodies: LS-C165200.
3
Bronchial Allergen Challenge of Patients with Atopic Asthma Triggers an Alarmin (IL-33, TSLP, and IL-25) Response in the Airways Epithelium and Submucosa. Wang W, Li Y, Lv Z, Chen Y, Li Y, Huang K, Corrigan CJ, Ying S. Journal of immunology (Baltimore, Md. : 1950). 2018 October;201:2221-2231. [Full Text Article] [PubMed:30185520] Related Antibodies: LS-C165200.

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Products
ELISA Kits (26)
Development Kit (3)
Sandwich (18)
Sandwich CLIA (5)
IL25 / IL17E (26)
Human (13)
Mouse (9)
Rat (4)
Product Group
DevKit Core (3)
1000 Wells (2)
12 x 8-Well Microstrips (3)
200 Wells (1)
96-Well Microplate (6)
96-Well Strip Plate (14)
No (26)
Cell Culture Supernatants (9)
Cell Lysates (7)
Plasma (23)
Serum (23)
Tissue Homogenates (7)
IL25 / IL17E ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
32 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$414
IL25 / IL17E ELISA Kit
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Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
IL25 / IL17E ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
IL25 / IL17E ELISA Kit
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Sandwich
96-Well Microplate
Human
0.41 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
IL25 / IL17E ELISA Kit
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Development Kit
200 Wells
Human
16 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Test/$180
IL25 / IL17E ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
IL25 / IL17E ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Mouse
63 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$534
IL25 / IL17E ELISA Kit
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Sandwich
96-Well Microplate
Mouse
49.16 - 4800 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
IL25 / IL17E ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
IL25 / IL17E ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Human
4 - 500 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$562
IL25 / IL17E ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$582
IL25 / IL17E ELISA Kit
Select
Development Kit
1000 Wells
Human
16 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Test/$540
IL25 / IL17E ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
250 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
IL25 / IL17E ELISA Kit
Select
Development Kit
1000 Wells
Human
32 - 2000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
IL25 / IL17E ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
IL25 / IL17E ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.3 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$582
IL25 / IL17E ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Mouse
1.37 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$871
IL25 / IL17E ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
1.37 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$851
IL25 / IL17E ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
1.37 - 1000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$911
IL25 / IL17E ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$750
IL25 / IL17E ELISA Kit
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Sandwich
96-Well Microplate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
IL25 / IL17E ELISA Kit
Select
Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
IL25 / IL17E ELISA Kit
Select
Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
IL25 / IL17E ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL25 / IL17E ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).