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IL3RA / CD123

interleukin 3 receptor, alpha (low affinity)

IL3RA / CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

Gene Name: interleukin 3 receptor, alpha (low affinity)
Family/Subfamily: Interleukin
Synonyms: IL3RA, CD123 antigen, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL3R, IL3RY, CD123, HIL-3Ra, IL-3R-alpha, IL-3RA, IL3RAY, IL3RX
Target Sequences: NM_002183 NP_002174.1 P26951

Publications (1)

1
Basophils and the T helper 2 environment can promote the development of lupus nephritis. Charles N, Hardwick D, Daugas E, Illei GG, Rivera J. Nature medicine. 2010 16:701-7. [PubMed:20512127] [PMC:PMC2909583] Related Antibodies: LS-C40981.

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Products
Antibodies (80)
Primary (80)
IL3RA / CD123 (80)
Human (63)
Mouse (24)
Rat (4)
Chimpanzee (3)
Orangutan (3)
IHC (8)
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WB (57)
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IP (7)
Peptide-ELISA (1)
rabbit (49)
mouse (30)
goat (1)
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IHCPlus (3)
IgG (8)
IgG1 (8)
IgG1,k (14)
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monoclonal mc (29)
polyclonal pc (51)
01 (1)
10B8E7 (1)
18N6B12 (1)
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8E11C5 (1)
IL3RA/1531 (3)
AF488 Conjugated (1)
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APC (3)
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p593 (1)
pTyr593 (1)
No (79)
Yes (1)
IL3RA / CD123 Antibody - Anti-IL3RA / CD123 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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IL3RA / CD123 Mouse anti-Human Monoclonal (aa200-305) (10B8E7) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
IL3RA / CD123 Antibody - Human peripheral blood lymphocytes stained with 6H6 PE and CD45RO PE/Cy5
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IL3RA / CD123 Mouse anti-Human Monoclonal (6H6) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$276
IL3RA / CD123 Antibody - IHC of paraffin-embedded ovarian cancer tissues using IL3RA mouse monoclonal antibody with DAB staining.
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IL3RA / CD123 Mouse anti-Human Monoclonal (aa200-305) (8E11C5) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$459
IL3RA / CD123 Antibody - Staining of TF-1 cells with Purified Mouse IgG1, K isotype control (open histogram) or Purified anti-human CD123 (6H6) (colored histogram) followed by PE Anti-Mouse IgG. Total viable cells were used for analysis.
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IL3RA / CD123 Mouse anti-Human Monoclonal (6H6) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P
Unconjugated
25 µg/$215; 100 µg/$255
IL3RA / CD123 Antibody - IHC of CD123 on FFPE Kikuchi-Fujimoto Disease tissue.
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IL3RA / CD123 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.1 ml/$332
IL3RA / CD123 Antibody - IHC of CD123 on FFPE Kikuchi-Fujimoto Disease tissue. This image was taken for the unmodified form of this product. Other forms have not been tested.
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IL3RA / CD123 Mouse anti-Human Monoclonal (Ready-to-Use) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$367
IL3RA / CD123 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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IL3RA / CD123 Goat anti-Human Polyclonal Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
IL3RA / CD123 Antibody - CD123 Antibody in Flow Cytometry (Flow)
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IL3RA / CD123 Mouse anti-Human Monoclonal (6H6) Antibody
Mouse, Human
Flo, IHC-Fr, IHC-P
Unconjugated
100 µg/$304
IL3RA / CD123 Antibody - IHC staining of FFPE human lymph node with CD123 antibody. HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9 for 10-20 min and allow to cool.
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IL3RA / CD123 Mouse anti-Human Monoclonal (IL3RA/1531) Antibody
Human
IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
IL3RA / CD123 Antibody - IHC staining of FFPE human lymph node with CD123 antibody. HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9 for 10-20 min and allow to cool.
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IL3RA / CD123 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (IL3RA/1531) Antibody
Human
IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
IL3RA / CD123 Antibody - Western blot of recombinant IL3RA / CD123.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL3RA / CD123 Rabbit anti-Mouse Polyclonal (aa167-331) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
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IL3RA / CD123 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IL3RA / CD123 Antibody - Western blot of recombinant IL3RA / CD123.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL3RA / CD123 Rabbit anti-Mouse Polyclonal (aa17-166) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
IL3RA / CD123 Antibody - Western blot of Human THP-1 . IL3RA antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL3RA / CD123 Rabbit anti-Human Polyclonal (aa51-100) Antibody
Human
WB
Unconjugated
100 µl/$424
IL3RA / CD123 Antibody - Western blot analysis of CD123 expression in MCF7 (A); NIH3T3 (B); PC12 (C) whole cell lysates.
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IL3RA / CD123 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
IL3RA / CD123 Antibody - Western blot of IL3RA Antibody with human 721_B Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL3RA / CD123 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
IL3RA / CD123 Antibody - Western blot of recombinant IL3RA / CD123.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL3RA / CD123 Rabbit anti-Human Polyclonal (aa19-157) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325
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IL3RA / CD123 Mouse anti-Human Monoclonal (6H6) Antibody
Human
Flo, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$302
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IL3RA / CD123 Mouse anti-Human Monoclonal (FITC) (6H6) Antibody
Human
Flo, IHC-Fr, IP, WB
FITC Conjugated
100 Tests/$337
IL3RA / CD123 Antibody - Surface staining of human peripheral blood with anti-CD123 (6H6) PE.
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IL3RA / CD123 Mouse anti-Human Monoclonal (PE) (6H6) Antibody
Human
Flo, IHC-Fr, IP, WB
PE Conjugated
100 Tests/$365
IL3RA / CD123 Antibody - Surface staining of human peripheral blood with anti-CD123 (6H6) APC.
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IL3RA / CD123 Mouse anti-Human Monoclonal (APC) (6H6) Antibody
Human
Flo, IHC-Fr, IP, WB
APC Conjugated
100 Tests/$365
IL3RA / CD123 Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
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IL3RA / CD123 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
IL3RA / CD123 Antibody - Surface staining of human peripheral blood with anti-CD123 (6H6) biotin.
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IL3RA / CD123 Mouse anti-Human Monoclonal (Biotin) (6H6) Antibody
Human
Flo, IHC-Fr, IP, WB
Biotin Conjugated
0.1 mg/$337
IL3RA / CD123 Antibody - Western blot analysis of extracts from RAW264.7 cells, treated with G-CSF (25ng/ml, 15mins), using IL3R (Ab-593) antibody.
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IL3RA / CD123 Rabbit anti-Human Polyclonal (p593) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
IL3RA / CD123 Antibody - P-peptide - + Immunohistochemical analysis of paraffin-embedded human brain tissue using IL3R (Phospho-Tyr593) antibody.
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IL3RA / CD123 Rabbit anti-Human Polyclonal (pTyr593) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).