Products
Research Areas
COVID-19
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
206-374-1102
Fax:
206-577-4565
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, Proforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

IL6 / Interleukin 6

interleukin 6 (interferon, beta 2)

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.

Gene Name: interleukin 6 (interferon, beta 2)
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL6, B-cell stimulatory factor 2, BSF-2, BSF2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, Interleukin-6, Interleukin BSF-2, IFNB2, B-cell differentiation factor, CDF, HSF, IL-6
Target Sequences: NM_000600 NP_000591.1 P05231

Publications (9)

1
Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice. Chen C, Liu Y, Liu Y, Zheng P. The Journal of clinical investigation. 2010 120:4091-101. (Mouse) [PubMed:20972332] [PMC:PMC2964994] Related Antibodies: LS-C7955.
2
Fetal skin as a pro-inflammatory organ: Evidence from a primate model of chorioamnionitis. Boonkasidecha S, Kannan PS, Kallapur SG, Jobe AH, Kemp MW. PloS one. 2017 September;12:e0184938. (Human) [Full Text Article] [PubMed:28957335] [PMC:PMC5619751] Related Antibodies: LS-B7482.
3
Contribution of the Interleukin-6/STAT-3 Signaling Pathway to Chondrogenic Differentiation of Human Mesenchymal Stem Cells. Kondo M, Yamaoka K, Sakata K, Sonomoto K, Lin L, Nakano K, Tanaka Y. Arthritis & rheumatology (Hoboken, N.J.). 2015 May;67:1250-60. [Full Text Article] [PubMed:25604648]
4
Oleoylethanolamide treatment reduces neurobehavioral deficits and brain pathology in a mouse model of Gulf War Illness. Joshi U, Evans JE, Joseph R, Emmerich T, Saltiel N, Lungmus C, Oberlin S, Langlois H, Ojo J, Mouzon B, Paris D, Mullan M, Jin C, Klimas N, Sullivan K, Crawford F, Abdullah L. Scientific reports. 2018 August;8:12921. [Full Text Article] [PubMed:30150699] [PMC:PMC6110778]
5
The Morphopathogenetic Aspects of Intraabdominal Adhesions in Children under One Year of Age. Junga A, Pilmane M, Abola Z, Volrats O. Medicina (Kaunas). 2019 August;55:E556. [Full Text Article] [PubMed:31480453] [PMC:PMC6780280] Related Antibodies: LS-B1582.
6
IL-6 release from muscles during exercise is stimulated by lactate-dependent protease activity. Pernille Hojman, Camilla Brolin, Nynne Nørgaard-Christensen, Christine Dethlefsen, Britt Lauenborg, Cecilie Køllner Olsen, Mette Marie Åbom, Thomas Krag, Julie Gehl, Bente Klarlund Pedersen. American journal of physiology. Endocrinology and metabolism. 2019 May;316:E940-E947. [Full Text Article] [PubMed:30779630]
7
Mystery Solved: Why Smoke Extract Worsens Disease in Smokers with Crohn's Disease and Not Ulcerative Colitis? Gut MAP!. Dania AlQasrawi, Latifa S Abdelli, Saleh A Naser. Microorganisms. 2020 May;8:666. [Full Text Article] [PubMed:32370298] [PMC:PMC7284734]
8
Effects of arginase inhibition via jugular infusion of N?-hydroxy-nor-l-arginine on metabolic and immune indices in lactating dairy cows. L Y Ding, Y F Wang, Y Z Shen, G Zhou, X Zhang, M Z Wang, J J Loor, J Zhang. Journal of dairy science. 2019 Apr;102:3310-3320. [Full Text Article] [PubMed:30738683]
9
Increased IL-6 expression precedes reliable viral detection in the rhesus macaque brain during acute SIV infection. Raja Mohan Gopalakrishnan, Malika Aid, Noe B Mercado, Caitlin Davis, Shaily Malik, Emma Geiger, Valerie Varner, Rhianna Jones, Steven E Bosinger , Cesar Piedra-Mora, Amanda J Martinot , Dan H Barouch , R Keith Reeves , C Sabrina Tan. JCI insight. 2021 Oct;6:e152013. [Full Text Article] [PubMed:34676832] [PMC:PMC8564899] Related Antibodies: LS-A9692.
more

☰ Filters
Antibodies (393)
ELISA Kits (104)
Proteins (85)
Competitive EIA (2)
Custom (1)
Development Kit (15)
Over-Expression Lysate (2)
Primary (387)
Recombinant (83)
Sandwich (74)
Sandwich CLIA (12)
Secondary (6)
IL6 / Interleukin 6 (582)
Human (203)
Mouse (110)
Rat (87)
Baboon (1)
Bovine (8)
Canine (3)
Chicken (6)
Cynomolgus (2)
Dog (12)
Goat (7)
Guinea pig (1)
Hamster (1)
Horse (5)
Monkey (31)
Pig (21)
Rabbit (15)
Rhesus monkey (18)
Sheep (26)
IHC (59)
IHC-Fr (3)
IHC-P (24)
WB (299)
Flo (36)
Bind (2)
Block (2)
ELISA (167)
Func (13)
ICC (15)
IF (14)
Inhb (1)
IP (26)
Neut (43)
Peptide-ELISA (1)
RIA (2)
SDS-PAGE (3)
SwELISA (5)
rabbit (208)
mouse (112)
goat (16)
chicken (2)
guinea pig (8)
rat (46)
sheep (1)
Product Group
Coronavirus Antibodies Proteins cDNAs (473)
Coronavirus Detection (103)
Cytokine Release Syndrome (576)
Cytokine Release Syndrome Antibodies (389)
Cytokine Release Syndrome Proteins (84)
DevKit Core (10)
DevKit DuoPlus (5)
ELISA Kits for Cytokine Release Syndrome Targets (103)
IHCPlus (16)
PathPlus Neuro (3)
IgG (137)
IgG1 (48)
IgG1,k (23)
IgG2a (11)
IgG2a,k (9)
IgG2b (4)
IgG2b,k (9)
IgM (2)
monoclonal mc (160)
polyclonal pc (233)
057 (1)
076 (1)
10E5 (1)
14 (1)
19 (1)
1B1-B10-D2 (2)
2A8-D8-C3 (1)
2F6H6 (1)
33A12.G9 (2)
3C1-C2-D11 (2)
4B6 (1)
5E1 (1)
6B4 IGH 54 (1)
6D9A1 (1)
72 (1)
7D9H6 (1)
8F4 (1)
AS12 (1)
AS16 (1)
AT1F10 (1)
AT1H6 (1)
AV129 (1)
B-E8 (2)
C8 (6)
CC310 (1)
KT105 (1)
mhK23 (1)
MP5-20F3 (13)
MP5-32C11 (5)
MQ2-13A5 (6)
MQ2-39C3 (4)
NYRhIL6 (2)
OTI2C9 (1)
OTI2G3 (2)
OTI3G9 (2)
OTI3H6 (2)
R508 (1)
1000 Wells (5)
12 x 8-Well Microstrips (6)
200 Wells (5)
96-Well Microplate (15)
96-Well Strip Plate (68)
Animal-free (2)
Antibody Pair and Standard (5)
AP Conjugated (11)
APC (15)
APC Conjugated (26)
Azide-free (11)
Biotin (NHS-LC) Conjugated (1)
Biotin Conjugated (53)
BSA-free (1)
Carrier-free (3)
Concentrated (4)
Cy3 Conjugated (15)
Cy7 Conjugated (15)
FITC Conjugated (36)
HRP Conjugated (28)
Low Endotoxin (3)
Magnetic beads Conjugated (1)
PE Conjugated (28)
Preservative Free (22)
Sepharose Conjugated (1)
Serum (1)
Unconjugated (178)
aa25-211 (26)
aa29-212 (26)
aa27-212 (18)
aa30-208 (18)
Internal (16)
aa21-211 (14)
aa30-212 (12)
aa18-207 (8)
aa27-241 (8)
aa27-55 (8)
aa195-211 (4)
aa26-208 (3)
aa195-212 (1)
No (575)
Yes (7)
Cell Culture Supernatants (52)
Cell Lysates (39)
Plasma (89)
Serum (89)
Tissue Homogenates (58)
Urine (1)
6His, N-terminus (3)
GST (2)
GST, N-terminus (1)
His (16)
His, N-Terminal (7)
His,C-terminus (1)
His-GST, N-terminus (3)
His-T7 (1)
Human IgG1 Fc (1)
Human IgG2 Fc (1)
Human Mutant IgG1 Fc (1)
Mouse Mutant IgG2a Fc (1)
Myc-DDK (Flag) (3)
Bovine (2)
Chicken (1)
Dog (3)
Human (38)
Monkey-Rhesus (1)
Mouse (18)
Pig (4)
Rabbit (2)
Rat (10)
Rhesus monkey (2)
Sheep (3)
293F Cells (6)
293T Cells (1)
CHO Cells (5)
E. coli (53)
HEK 293 Cells (8)
Human (2)
Wheat Germ Extract (2)
Yeast (4)
Purified (30)
Low endotoxin level (49)
Biologically active (34)
Animal-free (4)
IL6 / Interleukin 6 Antibody - Anti-IL-6 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Neuroscience
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
IL6 / Interleukin 6 Antibody - Anti-IL-6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Select
IL6 / Interleukin 6 Mouse anti-Human Monoclonal (6D9A1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$440
IL6 / Interleukin 6 Antibody - Anti-IL-6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Neuroscience
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$440
IL6 / Interleukin 6 Antibody - Anti-IL-6 antibody IHC of rat spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Neuroscience
IL6 / Interleukin 6 Mouse anti-Rat Monoclonal (10E5) Antibody
Rat
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$555
IL6 / Interleukin 6 Antibody - Anti-IL-6 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
IL6 / Interleukin 6 Antibody - 1:200 staining human breast carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$369; 200 µl/$411
Select
IL6 / Interleukin 6 Rat anti-Mouse Monoclonal (Azide-free) Antibody
Mouse
ELISA, Flo, IHC, Neut, WB
Unconjugated, Azide-free
500 µg/$740
IL6 / Interleukin 6 Antibody - Immunohistochemistry of paraffin-embedded human tonsil using IL6 antibody at dilution of 1:100 (40x lens).
Select
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
IL6 / Interleukin 6 Antibody - Immunohistochemistry with anti-IL-6 antibody showing nuclear positivity of islets of Langerhans (brown staining) and cytoplasmic staining in mouse pancreas at 10x and 20x (B & C). Staining was performed on Leica Bond system using the standard protocol. Formalin fixed/paraffin embedded tissue sections were subjected to antigen retrieval with E1 (Leica Microsystems) retrieval solution for 20 min and then incubated with rabbit anti-mouse IL-6 antibody at 1:50 dilution for 60 minutes. Biotinylated Anti-rabbit secondary antibody was used at 1:200 dilution to detect primary antibody. The reaction was developed using streptavidin-HRP conjugated compact polymer system and visualized with chromogen substrate, 3’3-diamino-benzidine substrate (DAB). The sections were then counterstained with hematoxylin to detect cell nuclei.
Select
IL6 / Interleukin 6 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, WB
Unconjugated
100 µg/$498
IL6 / Interleukin 6 Antibody - Anti-Human IL-6 Western Blot Reduced
Select
IL6 / Interleukin 6 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$297
Select
IL6 / Interleukin 6 Rabbit anti-Sheep Polyclonal (Serum) Antibody
Sheep
ELISA, WB
Unconjugated, Serum
0.1 ml/$523
IL6 / Interleukin 6 Antibody - IL-6 antibody (2C9) at 1:500000 + recombinant human IL-6.
Select
IL6 / Interleukin 6 Mouse anti-Human Monoclonal (OTI2C9) Antibody
Human
WB
Unconjugated
100 µl/$409
IL6 / Interleukin 6 Antibody - Western blot of recombinant IL6.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IL6 / Interleukin 6 Guinea pig anti-Rabbit Polyclonal (aa27-241) Antibody
Rabbit
WB
Unconjugated
100 µl/$297; 200 µl/$338; 500 µl/$475; 1 ml/$543
IL6 / Interleukin 6 Antibody - IL6 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal (aa27-55) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$376
Select
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$284; 100 µg/$348
IL6 / Interleukin 6 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$341
IL6 / Interleukin 6 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates, Urine
1 Plate/$644
IL6 / Interleukin 6 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$585
IL6 / Interleukin 6 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
3.12 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$809
IL6 / Interleukin 6 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Hamster
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$744
IL6 / Interleukin 6 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
IL6 / Interleukin 6 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$744
IL6 / Interleukin 6 ELISA Kit
Select
Development Kit
1000 Wells
Mouse
8 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1 Test/$540
IL6 / Interleukin 6 ELISA Kit
Select
Sandwich
96-Well Microplate
Rabbit
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Select
CHO Cells
Human Mutant IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$341
Viewing 1-25 of 582 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).