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IL8 / Interleukin 8

interleukin 8

Interleukin 8 (IL8), a member of the CXC chemokine family. This chemokine, is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.

Gene Name: interleukin 8
Family/Subfamily: Intercrine , Intercrine alpha
Synonyms: CXCL8, 3-10C, AMCF-I, B-ENAP, C-X-C motif chemokine 8, GCP-1, IL-8, IL8, Interleukin-8, K60, LECT, GCP1, LUCT, NAF, NAP1, Neutrophil-activating factor, Interleukin 8, Protein 3-10C, MDNCF, TSG-1, Emoctakin, LYNAP, MONAP, NAP-1, SCYB8, T-cell chemotactic factor
Target Sequences: NM_000584 NP_000575.1 P10145

Publications (6)

1
Unique early gene expression patterns in human adult-to-adult living donor liver grafts compared to deceased donor grafts. de Jonge J, Kurian S, Shaked A, Reddy KR, Hancock W, Salomon DR, Olthoff KM. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2009 9:758-72. (IHC) [PubMed:19353763] [PMC:PMC2734955]
2
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-?B-Snail signaling in glioma. Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, Wang X, Zhao C, Zhang H, Wang Y. Cancer biology & therapy. 2015 16:898-911. (IHC, WB; Human) [Full Text Article] [PubMed:25870011] [PMC:PMC4623112] Related Antibodies: LS-C104558.
3
Expression and secretion of the pro-inflammatory cytokine IL-8 is increased in colorectal cancer cells following the knockdown of non-erythroid spectrin aII. Anne Ackermann, Barbara Lafferton, Guido Plotz, Stefan Zeuzem, Angela Brieger. International journal of oncology. 2020 June;56:1551-1564. [Full Text Article] [PubMed:32236629] Related Antibodies: LS-C663556.
4
Free fatty acids promote degranulation of azurophil granules in neutrophils by inducing production of NADPH oxidase-derived reactive oxygen species in cows with subclinical ketosis. Yuxiang Song, Shang Jiang, Congyi Li, Juan J Loor, Qianming Jiang, Yuchen Yang, Xiancheng Feng, Siyuan Liu, Jiyuan He, Kexin Wang, Yunfei Li, Cai Zhang, Xiliang Du, Zhe Wang, Xinwei Li, Guowen Liu. Journal of dairy science. 2022 March;105:2473-2486. [Full Text Article] [PubMed:34998570]
5
LncRNA H19 aggravates TNF-a-induced inflammatory injury via TAK1 pathway in MH7A cells. Jialiang Yang, Yixuan Li, Lili Wang, Zhenchun Zhang, Zunzhong Li, Qian Jia. BioFactors (Oxford, England). 2020 September;46:813-820. [Full Text Article] [PubMed:32525617] Related Antibodies: LS-C104558.
6
Plexin-B1 activates NF- kappa B and IL-8 to promote a pro-angiogenic response in endothelial cells. Yang YH, Zhou H, Binmadi NO, Proia P, Basile JR. PloS one. 2011 6:e25826. [Full Text Article] [PubMed:22028792] [PMC:PMC3196529] Related Antibodies: LS-C8020.
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IL8 / Interleukin 8 Antibody - Western Blot (non-reducing) of IL-8 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL8 / Interleukin 8 Antibody - Anti-IL-8 antibody IHC of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal (5D8) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal (I8-60) Antibody
Human
ELISA, Neut, WB
Unconjugated
100 µg/$426; 500 µg/$740
IL8 / Interleukin 8 Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma reacted with IL8 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal (aa72-99) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Neut, WB
Unconjugated
500 µg/$688
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-Fr
Unconjugated
100 µg/$551; 500 µg/$1,375
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$741
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Microplate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$559
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$582
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$495
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
IL8 / Interleukin 8 Antibody - Western Blot; Sample: Recombinant IL8, Human.
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal (C4) Antibody
Human
WB
Unconjugated
100 µl/$292; 200 µl/$327; 500 µl/$443; 1 ml/$501; 2 ml/$626; 5 ml/$1,072
IL8 / Interleukin 8 Antibody - 1/100 staining human kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary antibody.
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL8 / Interleukin 8 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal (aa77-95) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$380
IL8 / Interleukin 8 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal (aa77-95) (Magnetic beads) Antibody
Human
IP
Magnetic beads Conjugated
100 µg/$399
IL8 / Interleukin 8 Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC-P
Unconjugated
50 µg/$460
IL8 / Interleukin 8 Antibody - Anti-Human IL-8 (CXCL8) Western Blot Unreduced
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$326
IL8 / Interleukin 8 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$719
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E. coli
His
13 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal (3E4D8) Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$380
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IL8 / Interleukin 8 Rabbit anti-Chicken Polyclonal Antibody
Chicken
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 413 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).