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IL9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Gene Name: | interleukin 9 |
Family/Subfamily: | IL-7/ IL-9 , not assigned-IL-7/ IL-9 |
Synonyms: | IL9, Cytokine P40, IL-9, Interleukin-9, HP40, p40 cytokine, Interleukin 9, T-cell growth factor P40, p40 |
Target Sequences: | NM_000590 NP_000581.1 P15248 |
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