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KCNA1 / Kv1.1

potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)

KCNA1 / Kv1.1 is a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Gene Name: potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
Family/Subfamily: Ion Channel , Potassium channel - Kv1 Shaker
Synonyms: KCNA1, EA1, AEMK, HBK1, KV1.1, HUK1, RCK1, MK1, RBK1, MBK1
Target Sequences: NM_000217 NP_000208.2 Q09470

☰ Filters
Products
Antibodies (37)
Primary (37)
KCNA1 / Kv1.1 (37)
Human (36)
Mouse (15)
Rat (14)
Bat (3)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Horse (3)
Monkey (3)
Pig (4)
IHC (12)
IHC-P (3)
WB (33)
ELISA (21)
ICC (1)
IF (2)
IP (1)
Peptide-ELISA (2)
rabbit (35)
mouse (2)
Product Group
PathPlus Neuro (2)
IgG (26)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (36)
2D8 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (23)
aa172-201 (7)
aa179-228 (4)
230-310 aa, Internal (1)
C-Terminus (1)
Internal (1)
aa239-288 (1)
aa256-305 (1)
aa298-343 (1)
aa465-481 (1)
No (37)
KCNA1 / Kv1.1 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa239-288) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
KCNA1 / Kv1.1 Antibody - Detection limit for recombinant GST tagged KCNA1 is 0.3 ng/ml as a capture antibody.
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KCNA1 / Kv1.1 Mouse anti-Human Monoclonal (2D8) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
KCNA1 / Kv1.1 Antibody - Anti-KCNA1 / Kv1.1 antibody IHC of human brain, cerebellum, Purkinje cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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Neuroscience
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa256-305) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
KCNA1 / Kv1.1 Antibody - KCNA1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human cerebellum tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, WB
Unconjugated
200 µl/$468
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
KCNA1 / Kv1.1 Antibody - WB of KCNA1 / Kv1.1 antibody. All lanes: Anti-KCNA1 at 0.5ug/ml. Lane 1: Rat Brain Tissue Lysate at 40ug. Lane 2: Rat Testis Tissue Lysate at 40ug. Lane 3: Rat Cardiac Muscle Tissue Lysate at 40ug. Lane 4: HELA Whole Cell Lysate at 40ug. Lane 5: U87 Whole Cell Lysate at 40ug. Lane 6: SHG Whole Cell Lysate at 40ug. Lane 7: NEURO Whole Cell Lysate at 40ug. Predicted bind size: 56KD. Observed bind size: 56KD.
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa465-481) Antibody
Mouse, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
KCNA1 / Kv1.1 Antibody - Immunofluorescent analysis of HepG2 cells using KCNA1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
KCNA1 / Kv1.1 Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using KCNA1 Polyclonal Antibody at dilution of 1:30.
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa298-343) Antibody
Mouse, Rat, Human
ICC, WB
Unconjugated
50 µl/$321; 100 µl/$403
KCNA1 / Kv1.1 Antibody - Western blot testing of 1) rat brain and 2) mouse brain lysate with KCNA1 antibody at 0.5ug/ml. Expected molecular weight: 56-85 kDa depending on glycosylation level.
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KCNA1 / Kv1.1 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µg/$575
KCNA1 / Kv1.1 Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using KCNA1 antibody.
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
KCNA1 / Kv1.1 Antibody - Western blot analysis of Human kidney cancer tissue, using KCNA1 Polyclonal Antibody at dilution of 1:600.
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KCNA1 / Kv1.1 Antibody - Western blot analysis of KCNA1 using anti-KCNA1 antibody. Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: rat brain tissue lysates,Lane 2: mouse brain tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-KCNA1 antigen affinity purified polyclonal antibody at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1% Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit with Tanon 5200 system. A specific band was detected for KCNA1 at approximately 75KD. The expected band size for KCNA1 is at 56KD.
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
KCNA1 / Kv1.1 Antibody - Western blot analysis of extracts from HeLa cells, MCF-7 cells and HuvEc cells, using KCNA1 antibody.
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
KCNA1 / Kv1.1 Antibody - Western blot of KV1.1 antibody
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (230-310 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KCNA1 / Kv1.1 Antibody - Western blot analysis of Kv1.1 expression in HEK293 (A); MCF7 (B) whole cell lysates.
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KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Rat, Pig, Human
IP, WB
Unconjugated
100 µl/$299
Viewing 1-25 of 37 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).