KCNA1 / Kv1.1

potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)

KCNA1 / Kv1.1 is a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

KCNA1 / Kv1.1 (5)

Publications

No (5)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human KCNA1 / Kv1.1 Protein (Recombinant 6His, N-terminus) (aa1-154) - LS-G57528

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human KCNA1 / Kv1.1 Protein (Recombinant GST) (Full Length) - LS-G29107

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

82.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human KCNA1 / Kv1.1 Protein (Recombinant GST, N-terminus) (aa410-495) - LS-G59046

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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KCNA1 / Kv1.1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98970

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.3 kDa

Price:

100 µg/$494

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Human KCNA1 / Kv1.1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79573

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.3 kDa

Price:

20 µg/$150

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