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KCNA2 / Kv1.2

potassium voltage-gated channel, shaker-related subfamily, member 2

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.

Gene Name: potassium voltage-gated channel, shaker-related subfamily, member 2
Family/Subfamily: Ion Channel , Potassium channel - Kv1 Shaker
Synonyms: KCNA2, HBK5, KV1.2, HuK4, MK2, NGK1, RBK2, HK4, HUKIV
Target Sequences: NM_004974 NP_004965.1 P16389

Publications (2)

1
Specific antibodies to the external vestibule of voltage-gated potassium channels block current. Zhou BY, Ma W, Huang XY. The Journal of general physiology. 1998 111:555-63. [PubMed:9524138] [PMC:PMC2217123]
2
Postsynaptic density-95 scaffolding of Shaker-type K channels in smooth muscle cells regulates the diameter of cerebral arteries. Joseph BK, Thakali KM, Pathan AR, Kang E, Rusch NJ, Rhee SW. The Journal of physiology. 2011 589:5143-52. [PubMed:21911612] [PMC:PMC3225670]

☰ Filters
Antibodies (23)
Proteins (3)
Over-Expression Lysate (2)
Primary (23)
Recombinant (1)
KCNA2 / Kv1.2 (26)
Human (17)
Mouse (6)
Rat (10)
Bat (1)
Bovine (1)
Chicken (1)
Dog (1)
Guinea pig (1)
Hamster (1)
Horse (1)
Pig (1)
Rabbit (1)
Sheep (1)
IHC (13)
IHC-P (2)
WB (23)
ELISA (9)
ICC (1)
IF (9)
rabbit (17)
mouse (6)
Product Group
PathPlus Neuro (1)
IgG (10)
IgG2b,k (6)
monoclonal mc (6)
polyclonal pc (17)
APC Conjugated (2)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (13)
aa451-479 (7)
C-Terminus (3)
aa466-499 (1)
No (26)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
KCNA2 / Kv1.2 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Neuroscience
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC-P, WB
Unconjugated
50 µl/$460
Select
KCNA2 / Kv1.2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$379
Select
KCNA2 / Kv1.2 Mouse anti-Rat Monoclonal Antibody
Rat
IF, IHC, WB
Unconjugated
100 µg/$880
Select
KCNA2 / Kv1.2 Mouse anti-Rat Monoclonal (HRP) Antibody
Rat
IF, IHC, WB
HRP Conjugated
100 µl/$1,094
Select
KCNA2 / Kv1.2 Mouse anti-Rat Monoclonal (Biotin) Antibody
Rat
IF, IHC, WB
Biotin Conjugated
100 µl/$1,094
Select
KCNA2 / Kv1.2 Mouse anti-Rat Monoclonal (FITC) Antibody
Rat
IF, IHC, WB
FITC Conjugated
100 µl/$1,094
Select
KCNA2 / Kv1.2 Mouse anti-Rat Monoclonal (APC) Antibody
Rat
IF, IHC, WB
APC Conjugated
100 µl/$1,094
Select
KCNA2 / Kv1.2 Mouse anti-Rat Monoclonal (PE) Antibody
Rat
IF, IHC, WB
PE Conjugated
100 µl/$1,094
KCNA2 / Kv1.2 Antibody
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal (aa451-479) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal (aa451-479) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal (aa451-479) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal (aa451-479) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal (aa451-479) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal (aa451-479) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
KCNA2 / Kv1.2 Antibody - KCNA2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal (aa451-479) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$440; 100 µg/$480
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$440; 200 µl/$468
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$466
KCNA2 / Kv1.2 Antibody
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$575
KCNA2 / Kv1.2 Antibody - Kv1.2 antibody Western blot. All lanes: Anti Kv1.2 at 0.5 ug/ml. Lane 1: Rat Kidney Tissue Lysate at 50 ug. Lane 2: Rat Brain Tissue Lysate at 50 ug. Lane 3: Mouse Brain Tissue Lysate at 50 ug. Lane 4: Mouse Kidney Tissue Lysate at 50 ug. Predicted band size: 57 kD. Observed band size: 57 kD.
Select
KCNA2 / Kv1.2 Rabbit anti-Human Polyclonal (aa466-499) Antibody
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
HEK 293 Cells
Myc-DDK (Flag)
56.5 kDa
20 µg/$1,107
Select
HEK 293 Cells
Myc-DDK (Flag)
56.5 kDa
100 µg/$710
Viewing 1-25 of 26 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).