Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.
Gene Name: | potassium inwardly-rectifying channel, subfamily J, member 2 |
Family/Subfamily: | Ion Channel , Potassium channel - inward-rectifying |
Synonyms: | KCNJ2, ATFB9, HHBIRK1, IRK1, KIR2.1, LQT7, HIRK1, IRK-1, HHIRK1, SQT3 |
Target Sequences: | NM_000891 NP_000882.1 P63252 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.