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Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.
Gene Name: | klotho beta |
Synonyms: | KLB, BetaKlotho, Beta-klotho, BKL, Klotho beta, Klotho beta like, Klotho beta-like protein |
Target Sequences: | AA010359 Q86Z14 Q86Z14 |
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