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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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KLK3 / PSA
kallikrein-related peptidase 3
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Seum levels of KLK3 (also known as PSA) are useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
| Gene Name: | kallikrein-related peptidase 3 |
| Family/Subfamily: | Protease , Serine S1 |
| Synonyms: | KLK3, APS, Gamma-seminoprotein, Kallikrein-3, Kallikrein-related peptidase 3, P-30 antigen, Prostate specific antigen, Prostate-specific antigen, PSA, Semenogelase, KLK2A1, Seminin |
| Target Sequences: | NM_001648 NP_001639.1 P07288 |
Publications (1)
1
Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells. Morrissey C, Gallis B, Solazzi JW, Kim BJ, Gulati R, Vakar-Lopez F, Goodlett DR, Vessella RL, Sasaki T. Anti-cancer drugs. 2010 21:423-32. (WB)
[PubMed:20130467]
[PMC:PMC2953769]
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(3)
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KLK3 / PSA
(285)
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Human
(247)
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(76)
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(55)
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(7)
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(7)
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IgG
(49)
IgG1
(76)
IgG1,k
(38)
IgG2a
(32)
IgG2a,k
(3)
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(4)
IgG2b,k
(1)
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(2)
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(1)
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monoclonal mc
(175)
polyclonal pc
(63)
recombinant monoclonal rmc
(4)
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(1)
1.B.903
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113
(1)
14E7-E5
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B499
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(3)
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(2)
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(2)
50-130 aa, Internal
(1)
C Terminus
(1)
Leu106
(1)
aa194-261
(1)
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(1)
aa81-130
(1)
Publications
No
(285)
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(1)
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(7)
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(4)
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(22)
Serum
(22)
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(9)
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(4)
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(2)
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(1)
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(3)
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(3)
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(14)
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(1)
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293T Cells
(1)
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(4)
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(3)
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(1)
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(3)
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(2)
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(1)
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Purified
(4)
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Low endotoxin level
(5)
KLK3 / PSA Mouse anti-Human Monoclonal (aa26-251) (5A11E2) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
KLK3 / PSA Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (C3F12) Antibody
Human
ELISPOT, Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
Sandwich
96-Well Microplate
Human
10.24 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
E. coli
His
26.3 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
Sandwich
96-Well Microplate
Rat
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Microplate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Microplate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$675
KLK3 / PSA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (1A7) Antibody
Human
ELISPOT, Flo, ICC, IHC, IHC-Fr, IHC-P
Unconjugated
100 µg/$485
KLK3 / PSA Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
1 mg/$392
Cancer Pathology
Cancer
KLK3 / PSA Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC-P, WB
Unconjugated
50 µl/$460
KLK3 / PSA Mouse anti-Human Monoclonal (aa220-250) Antibody
Human
WB
Unconjugated
0.1 ml/$393
KLK3 / PSA Rabbit anti-Human Polyclonal (50-130 aa, Internal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (3E6) Antibody
Human
ELISPOT, Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
KLK3 / PSA Mouse anti-Human Monoclonal (Biotin) (A67-B/E3) Antibody
Human
ELISA, IHC-P, WB
Biotin Conjugated
0.1 mg/$326
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (2B7) Antibody
Human
ELISA, Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
Cancer Pathology
Cancer
KLK3 / PSA Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, IRMA
Unconjugated
0.1 mg/$460
KLK3 / PSA Mouse anti-Human Monoclonal (214) Antibody
Human
ELISA
Unconjugated
1 mg/$712
KLK3 / PSA Mouse anti-Human Monoclonal (AT1D10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
KLK3 / PSA Mouse anti-Human Monoclonal (A67-B/E3) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
KLK3 / PSA Mouse anti-Human Monoclonal (Azide-free, BSA-free) (A67-B/E3) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
KLK3 / PSA Mouse anti-Human Monoclonal (KLK3/801 + KLK3/1248) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
Sandwich
96-Well Strip Plate
Human
0.2 - 12.5 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
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product results
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